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biochemical studies of pigments from a pathogenic fungus microsporum cookei. v. evidence for the transmembrane permeability of xanthomegnin across phospholipid bilayer membranes.direct evidence is provided for the transmembrane permeation of xanthomegnin across phospholipid bilayer membranes using ascorbate-loaded liposomes. this process may be associated with an uncoupling effect on the oxidative phosphorylation of mitochondria.1978212291
[research of keratinophiles in the soil and their effects on human cutaneous pathology in the lyons area].between 1967 and 1977, the systematic research of keratinophiles of the ground in a radius of 30--50 km around lyon, has shown the ubiquitarian predominance of microsporum nanum, which is probably the most ancient occupant of the ground. the most intensive areas of human and animal occupation in the rhodanian tract show the predominance of microsporum gypseum, which is scarcely found in man. sporadic localizations, tightly limites, bound to cirulcation axes and international gathering, let us de ...1979488487
electron microscopic evidence of phosfon d-induced alterations in the membranes of the dermatophytic fungus microsporum cookei.the dermatophytic fungus microsporum cookei was cultivated for 24 h in the presence of subinhibitory and inhibitory concentrations (50 and 100 micrograms/ml) of phosfon d, a growth retardant for higher plants also affecting fungal development, and its toxic effects were examined at the ultrastructural level. in both treatments, phosfon d attacked the membranes, whose structural integrity was clearly compromised with damage of particular severity to mitochondria, nuclei and endoplasmic reticulum. ...1979530091
isolation of keratomycetes from the soil of wild animal cages and enclosures in the zoo of the parco nazionale d'abruzzo, italy.the keratinophilic fungi present in the soil of wild animal cages and enclosures in the zoo of the "parco nazionale d'abruzzo", at pescasseroli, italy were studied. the goal of the investigation was to determine what species of such fungi existed in wild animal habitats in that area and what variation there may be in their frequency in connection with the seasons. the most prevalent fungus was trichophyton ajelloi, followed in decreasing order by the chrysosporium species (c. keratinophilum, c. ...1978572094
genus microsporum dermatophytes in eastern bohemia.the authors presented a taxonomic survey of dermatophytes of the genus microsporum. from the 19 species described so far, they isolated ten species in the region of eastern bohemia. only the species microsporum cookei and m. gypsem are considered to be endemic species. the remaining are regarded as imported dermatophytes which are not able to maintain their existence permanently in the conditions of the mentioned region. data on the findings of the individual species were completed by the author ...19761034655
the occurrence of keratinophilic fungi in sewage sludge from egypt.the keratinophilic fungi of 40 sewage sludge samples from upper egypt were studied using a goat hair-baiting technique. 43 species representing 22 genera were isolated, 17 species of which were dermatophytes and closely related fungi: chrysosporium state of arthroderma tuberculatum, c. asperatum, c. georgii, c. indicum, c. keratinophilum, c. pseudomerdarium, c. queenslandicum, chrysosporium state of thielavia sepedonium, c. tropicum, microsporum cookei, m. gypseum, myceliophthora anamorph of cor ...19901693678
taxonomic study of keratinophilic fungi isolated from soil and some mammals in france.in france, most of the researches have showed the distribution of dermatophytes and other keratinophilic fungi in the soil and in the coat of wild mammals. during these last years, we have also practiced numerous investigations about the distribution of such fungi. the isolated species are: trichophyton mentagrophytes, trichophyton terrestre, trichophyton ajelloï, trichophyton simii, microsporum gypseum, microsporum cookei, microsporum nanum, microsporum persicolor, anixiopsis stercoraria, chrys ...19882454405
[survey of keratinophilic fungi from soils and mating behaviour of microsporum canis from human ringworm cases in hokkaido prefecture in japan].from 383 (38.3%) of a total 1000 of soil samples, collected from hokkaido prefecture, keratinophilic fungi have been isolated using hair baiting technique. the fungi isolated were as follows: 318 strains of trichophyton ajelloi (including 90 strains of arthroderma uncinatum), 59 of microsporum cookei (including 13 of nannizzia cajetani), 32 of chrysosporium keratinophilum, 23 of c. tropicum, 15 of chrysosporium anamorph of a. tuberculatum, 6 of t. terrestre (including 3 of a. insingulare and one ...19883384396
biochemical studies of pigments from the pathogenic fungus, microsporum cookei. 19734271697
comparative studies on ultrastructure of the pigmented and albino hyphae of microsporum cookei. 19704915339
incompatibility in microsporum cookei. 19715102873
an unusual variant of microsporum cookei. 19715135088
isolation of microsporum cookei from a human case. 19715165166
[observations on a case of microsporum cookei parasitic on a dog-faced baboon (papio papio)]. 19665336380
microsporum cookei ajello in an eczematous skin lesion. 19695407930
digestion process of microsporum cookei spore wall by snail enzyme: scanning electron microscopic examination. 19705431165
separation of quinone pigments from microsporum cookei by thin-layer chromatography. 19705431166
effect of naphthoquinone pigment, xanthomegnin from microsporum cookei on the respiration of rat liver mitochondria. 19705451999
[microsporum cookei as the pathogenetic agent of microsporia superficialis]. 19675589735
[microsporum cookei induced spontaneous laboratory dermatomycosis]. 19685666462
[microsporum cookei. incidence of its isolation from wild brazilian rodents]. 19655827696
[mixed infection by trichophyton verrucosum and microsporum cookei in man]. 19665917938
[3 positive results for microsporum cookei ajello 1959 in skin lesions of man]. 19665961473
investigation of keratinophilic fungi from soils in western australia a preliminary survey.in order to determine which species of geophilic dermatophytes were present in western australian soils 299 samples were investigated. these samples were collected from a range of locations, 208 towns throughout the state and 91 samples from the perth metropolitan area. most samples were collected from areas frequented by people and animals, such as home gardens, parks and animal yards. of the total 299 soils, 271 (90.6%) yielded keratinophilic fungi. a total of 181 dermatophytes were isolated, ...19806162100
antifungal properties of some pyrazolyl-alkyl-sulfides. electron microscopic evidence in two dermatophytes and candida albicans.four 5-amino-4-alkylthio-pyrazoles were synthesized and their antifungal activity was evaluated in vitro in trichophyton mentagrophytes, microsporum cookei and candida albicans. the compounds slightly influenced the growth kinetics of the yeast, but at concentrations ranging from 20 to 40 micrograms/ml completely prevented the mycelial growth of the two dermatophytes cultivated on sabouraud's agar medium. an electron microscopic study, undertaken by using the most active compound, showed that in ...19817017418
phospholipid and fatty acid composition of microsporum cookei: effect of exogenous unsaturated fatty acids. 19817323910
microsporum cookei as the suspected cause of ringworm in a dog. 19817336541
[the occurrence of keratinolytic fungi in the polluted environment of the labedy district in gliwice].this study was undertaken to find relationships between the degree of bacteriological contamination with qualitative composition of potentially pathogenic keratinolytic fungal population in soil, sediment and air samples from the labedy district in gliwice (poland). the examined soil samples were characterized by the predominance of botryotrichum piluliferum, chrysosporium anamorph of arthroderma curreyi, myceliophthora anamorph of ctenomyces serratus, chrysosporium pannicola and trichphyton aje ...19947792523
partial characterization of proteolytic enzymes of microsporum canis and microsporum cookei.characterization by proteinase inhibitors of the enzymes produced by microsporum spp. revealed that microsporum canis and microsporum cookei produce serine proteinase(s), but only m. canis expresses aspartic and cysteine proteinases and probably a metalloproteinase. both m. canis and m. cookei expressed metalloelastinolytic proteinases. all the proteinase types have been implicated in the pathogenicity of a wide range of microorganisms.19969009645
isozyme variation within and among populations of microsporum species.isozyme variation among 54 isolates of microsporum canis, 18 microsporum cookei isolates and two diheterospora isolates were studied using starch gel electrophoresis. of eight enzymes examined, four were polymorphic (est, g6p, mdh and pep), having from two to four electrophoretic forms. within each species, consistent and reproducible isozyme patterns of the eight enzyme systems were obtained. phenotypic diversity (h) in m. canis was higher than in m. cookei (h = 0.459 and h = 0.408 respectively ...19989919894
epidemiology of dermatomycoses of humans in central poland. part v. tinea corporis.the total number of dermatophytoses (7393) included 2204 (29.8%) cases of tinea glabrosa. etiological factors in descending order were: microsporum canis (23.5%), trichophyton mentagrophytes var. granulosum (21.6%), trichophyton rubrum (17.8%), trichophyton tonsurans (10.4%), epidermophyton floccosum (7.7%), t. mentagrophytes var. quinckeanum (6.0%), microsporum gypseum (5.3%), trichophyton violaceum (3.7%), t. mentagrophytes var. interdigitale (2.3%), microsporum equinum (0.7%), trichophyton ve ...199910680444
keratinomyces ajelloi and microsporum cookei in norwegian soil. 196113762392
the ascigerous state of microsporum cookei. 196113859869
[microsporum cookei: its isolation from brazilian wild rodents]. 196213877281
[1st isolation of microsporum cookei ajello 1959 in the territory of czechoslovakia]. 196213906155
[isolation of microsporum cookei in poland]. 196213986276
the pigments of microsporum cookei. 196214034105
[the isolation of keratinomyces ajelloi, trichophyton terrestre, microsporum gypseum and microsporum cookei from soil]. 196314063118
a survey on the pathogenic fungi in soil samples of potted plants from sari hospitals, iran.a total of 23 soil samples of potted plants was collected from hospitals in sari, iran. each sample contained approximately 200 g soil, taken from a depth of 0-10 cm of the pots. samples were analysed by two different methods. (1) culture on sabouraud's dextrose agar medium containing chloramphenicol (sc); cultured fungi were identified by macroscopic and microscopic characterization. (2) the hair-baiting technique (hbt) was used to isolate the keratinophilic fungi. after culture on sc medium, 1 ...200415350715
seasonal 4-year investigation into the role of the alpine marmot (marmota marmota) as a carrier of zoophilic dermatophytes.two hundred and six samples of alpine marmot (mamota marmota) hair (148 from adults and 58 from young subjects), 102 soil samples from the entrances to the burrows of the above individuals and 20 control specimens (obtained from adjoining areas away from the burrow systems where the rodents are not usually present) were examined from may 1994 to september 1997. seventy-five isolates belonging to six species of dermatophytes were found in 69 of the 206 hair samples examined (33.5%). two species w ...200516110784
dermatophytes, related keratinophilic and opportunistic fungi in indoor dust of houses and hospitals.dermatophytes, related keratinophilic and opportunistic fungi were isolated from indoor dust samples of 46 hospitals and 47 houses in kanpur. a total of 19 fungi represented by 11 genera were isolated by the hair-baiting technique from 230 and 235 samples from hospitals and houses respectively. the isolated fungi are acremonium implicatum (indian type culture collection) itcc 5266, a. strictum (germplasm centre for keratinophilic fungi) gpck 1137, aphanoascus fulvescens gpck 1081, arthroderma si ...200919584506
isolation of fungi from soil using the keratin-baiting technique.of 236 soil samples baited with wool, some 71.2% (168) produced fungal growth. gliocladium (25.0%), paecilomyces (14.8%), trichophyton (11.9%) species were the most prevalent in soil moistened with sterile distilled water (sdw) containing antibiotics. on the other hand, in soil moistened with sdw only, trichophyton (32.6%), paecilomyces (27.5%), diheterospora (16.5%), gliocladium (13.6%) and fusarium (13.1%) species were more common. of the known potential pathogens, the paecilomyces and fusariu ...199620882458
antidermatophytic action of resorcinol derivatives: ultrastructural evidence of the activity of phenylethyl resorcinol against microsporum gypseum.in this work, we evaluated the antidermatophytic activities of three resorcinol derivatives that have a history of use in dermo-cosmetic applications to discover molecules with multiple dermatological activities (i.e., multi-target drugs), thereby reducing the cost and time necessary for new drug development. the antidermatophytic activities of the three skin lighteners were evaluated relative to the known antifungal drug fluconazole on nine dermatophytes responsible for the most common dermatom ...201627706019
a multi-target approach toward the development of novel candidates for antidermatophytic activity: ultrastructural evidence on α-bisabolol-treated microsporum gypseum.multi-target strategies are directed toward targets that are unrelated (or distantly related) and can create opportunities to address different pathologies. the antidermatophytic activities of nine natural skin lighteners: α-bisabolol, kojic acid, β-arbutin, azelaic acid, hydroquinone, nicotinamide, glycine, glutathione and ascorbyl tetraisopalmitate, were evaluated, in comparison with the known antifungal drug fluconazole, on nine dermatophytes responsible for the most common dermatomycoses: mi ...201526132903
study of diseases of the grey squirrel (sciurus carolinensis) in italy. first isolation of the dermatophyte microsporum cookei.the ecological risks connected with the introduction of the north american grey squirrel (sciurus carolinensis) in italy are many. of particular importance is the conservation of the native red squirrel (s. vulgaris) population, since the experience from the british isles showed that where the grey squirrel was introduced, the autochthonous red squirrel became extinct. to determine the health status of grey squirrels trapped and euthanasized during an eradication campaign in the piedmont region, ...199910200938
antifungal activity of some 2,2':5',2"-terthiophene derivatives.the dermatophyte microsporum cookei ajello was treated with nine new natural and synthetic 2,2':5',2"-terthiophenes to determine their possible antifungal activity. in the dark the thiophenes were inactive, while when photoactivated with uv-a they induced a remarkable reduction in the growth rate of the fungus. the only exception was (e)-n-(2-methylpropyl)-3-(2,2':5',2"-terthien-5-yl)-propenamide , which was not fungistatic even at the highest dose tested (24 microm). the more active compounds w ...19947746300
isolation of dermatophytes and correlated species from the soil of public gardens and parks in rome.looking for dermatophytes and other keratinophilic fungi in the soil of parks and gardens in large towns is very interesting because of the relationship between the number of people living in the area and the presence of such fungi in the soil. as compared with other cities in italy, rome offers prime conditions for this kind of research. it has a high population density (10,000 inhabitants per sq/km2), and many parks and gardens, where it is possible to carry out soil studies. it was noted that ...19807423331
electron microscopy of microsporum cookei after 'in vitro' treatment with protoanemonin: a combined sem and tem study.the ranunculaceous derivative protoanemonin (pra) was studied as an antifungal agent on the dermatophyte microsporum cookei. the ultrastructural changes that pra brought about in this fungus were observed with both the transmission and scanning electron microscopes. the main anomalies noted were abnormally shaped hyphae and within the cytoplasm, multimembranous bodies which were irregular in shape and size, and tubules of 25 and 60 nm in diameters. mitochondria, nuclei and vacuoles were also var ...19892615800
ultraviolet-mediated antimycotic activity of alpha-terthienyl on microsporum cookei.alpha-terthienyl (alpha-t) in the presence of uv-a irradiation reduced the growth rate of microsporum cookei. in the dark, alpha-t accumulated in small diffuse vacuoles within the hyphae. after uv-a treatment, alpha-t caused damage to the membranes of the nucleus, mitochondria and endoplasmic reticulum. plasmolytic and autolytic changes occurred resulting in plasma membrane breakage and cell wall aberrations. uv-a activated alpha-t would appear to target membrane proteins.19902093120
biochemical studies of pigments from a pathogenic fungus microsporum cookei. iii. comparison of the effects of xanthomegnin and o-methylxanthomegnin on the oxidative phosphorylation of rat liver mitochondria.the effects of xanthomegnin and o-methylxanthomegnin on the oxidative phosphorylation of rat liver mitochondria were compared. the n-octanol/water partition coefficient of xanthomegnin was markedly enhanced by o-methylation, but o-methylation of xanthomegnin reduced the uncoupling effect on the respiratory system of mitochondria. analogous results were obtained in the uncoupling action of 5-hydroxy-1, 4-naphthoquinone (juglone) and 5-methoxy-1, 4-naphthoquinone (o-methyljuglone) on the oxidative ...1976939756
fungal toxicity of phosfon d and its reversion by lipids.the growth retardant phosfon d inhibits the growth of some yeasts and human pathogenic filamentous fungi. the toxic effects of the compound on the dermatophyte microsporum cookei were completely reversed by adding ergosterol and oleic acid to the medium. the significance of these findings is discussed.1978666296
an unusual lipid in the human pathogenic fungus epidermophyton floccosum.the dermatophyte epidermophyton floccosum contains an unusual lipid characterized as 1(3),2-diacylglyceryl-3(1)-o-4'-(n,n,n-trimethyl)homoserine. its concentration in e. floccosum is approx. 15% of the polar lipids. the role of this lipid in the biosynthesis of polar lipids and fatty acids is not yet known. however, it is interesting from a chemotaxonomic viewpoint that the lipids from two other genera of dermatophyte, microsporum cookei and trichophyton rubrum do not contain this novel lipid.1979486519
biochemical studies of pigments from a pathogenic fungus; microsporum cookei. vi. formation of a xanthomegnin-bypass to the mitochondrial electron transport system. 1979223869
microsporum mirabile and its teleomorph arthroderma mirabile, a new dermatophyte species in the m. cookei clade.a novel dermatophyte species is described in the microsporum cookei clade. it differs significantly from known taxa in the two molecular markers analyzed, i.e., its and partial +¦-tubulin (bt2). morphologically the species was characterized by smooth- or only slightly rough-walled conidia, but isolates rapidly became pleomorphic with sparse, smooth- and thick-walled macroconidia in addition to microconidia. a teleomorph was found after mating.201121838616
antidermatophytic activity of pyrazolo[3,4-c]isothiazoles: a preliminary approach on 4-chlorophenyl derivative for evaluation of mutagenic and clastogenic effects on bacteria and human chromosomes in vitro.the antifungal activity of eight pyrazolo[3,4-c]isothiazole derivatives was evaluated on five dermatophytes: three were of an anthropophilic species (i.e., epidermophyton floccosum, trichophyton rubrum, and trichophyton tonsurans) and two were of a geophilic species (i.e., microsporum gypseum and nannizzia cajetani). the new compounds proved to be unlikely effective in inhibiting the growth of the different strains. in general, the fungi parasitic on man were more sensitive than the geophilic sp ...201121649488
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