Publications

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blastomycosis in an african lion.using fluorescent antibody techniques, blastomyces dermatitidis was identified in pyogranulomatous lesions in the lungs, mediastinum, trachea, and cerebrum of an african lion (panthera leo). clinical signs included anorexia and dry inspiratory rales. signs of nervous system dysfunction were not reported prior to death even though a large lesion was found in the cerebrum at necropsy. the lion was shipped from a geographic area where b dermatitidis infection is endemic. it was evident from histolo ...19807451322
disseminated blastomycosis in two california sea lions (zalophus californianus).two captive california sea lions (zalophus californianus) from different facilities were diagnosed with disseminated blastomycosis. the first, a 12-yr-old male, died after a 3-wk history of progressive anorexia and lethargy. gross examination revealed acute jejunitis with focal perforation and associated peritonitis, along with severe purulent bronchopneumonia. the second, a 15-yr-old female, was euthanized after a 2-wk history of severe cutaneous ulceration and declining clinical condition. gro ...200010982135
comparison of seven blastomyces dermatitidis antigens for the detection of antibodies in humans with occupationally acquired blastomycosis.yeast phase lysate antigens, prepared from seven isolates of blastomyces dermatitidis (dogs, t-58, m-98; human, le; soil, s; sea lion, sl; polar bear, pb; cat, c) were assayed by enzyme-linked immunosorbent assay (elisa) to detect antibodies in human sera. the sera were from individuals potentially exposed to b. dermatitidis while working on a prairie dog relocation project in colorado. all antigens exhibited greatest reactivity with three specimens in two separate assays. absorbance values rang ...200212572716
blastomycosis in nondomestic felids.blastomycosis was diagnosed in six nondomestic felids from eastern tennessee, including two asian lions (panthera leo persicus), one african lion (panthera leo), one siberian tiger (panthera tigris), one cheetah (acinonyx jubatus), and one snow leopard (panthera uncia). clinical signs included lethargy, anorexia, weight loss, dyspnea, sneezing. ataxia, and paresis. variable nonspecific changes included leukocytosis, monocytosis, moderate left shift of neutrophils, moderate hypercalcemia, hyperpr ...200314582783
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