Publications

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an environmentally regulated pilus-like appendage involved in campylobacter pathogenesis.examination of strains of campylobacter jejuni, campylobacter coli, and campylobacter fetus by electron microscopy revealed that they produced peritrichous pilus-like appendages when the bacteria were grown in the presence of bile salts. various bile-salt supplements were used and it was found that deoxycholate and chenodeoxycholic acid caused a significant enhancement of pilus production and resulted in a highly aggregative phenotype. morphologically, the pili were between 4 and 7 nm in width a ...19968793884
ferret as a potential reservoir for human campylobacteriosis.a survey was conducted to determine the frequency of campylobacter fetus subsp jejuni in feces of ferrets purchased for use in biomedical research. over a 12-month period, 168 ferrets from 2 commercial breeders were examined by bacteriologic cultural procedures for campylobacter spp; 61% were culturally positive for c fetus subsp jejuni. in a therapeutic trial with 16 ferrets shedding c fetus subsp jejuni in feces, erythromycin given orally failed to eliminate intestinal carriage of the organism ...19836870007
proliferative colitis in ferrets.during a 4-month period, 31 of 156 ferrets (mustela putorius) in a biomedical research program developed protracted diarrhea. clinical signs were green mucohemorrhagic fecal material, partially prolapsed rectum, anorexia, body weight loss, and dehydration. nine of the affected animals were necropsied. on gross examination, the descending colon was grossly thick and histologically characterized by marked proliferation of the mucosa, relatively few goblet cells, mixed inflammatory cell infiltrate, ...19827091850
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