| feline viruses in wildcats from scotland. | few data are available on the prevalence of feline viruses in european wildcats (felis silvestris). previous surveys have indicated that wildcats may be infected with the common viruses of domestic cats, apart from feline immunodeficiency virus (fiv). in the present study, 50 wildcats trapped throughout scotland (uk) between august 1992 and january 1997 were tested for evidence of viral infection. all were negative for fiv by several serological or virological methods. by contrast, 10% of the ca ... | 1999 | 10073361 |
| feline leukemia virus in a captive bobcat. | an 11-mo-old captive-bred male neutered bobcat (felis rufus) presented with lethargy, anorexia, leukopenia, neutropenia, lymphopenia, and nonregenerative anemia. the animal was diagnosed as feline leukemia virus (felv) positive by immunofluorescent antibody and enzyme-linked immunosorbant assay (elisa) testing. it died despite supportive care. pathologic examination revealed multifocal non-suppurative encephalitis, diffuse interstitial pneumonia, multifocal hepatocellular necrosis, non-suppurati ... | 2001 | 11272497 |
| quantification of endogenous and exogenous feline leukemia virus sequences by real-time pcr assays. | endogenous retroviruses are integrated in the genome of most vertebrates. they represent footprints of ancient retroviral infection and are vertically transmitted from parents to their offspring. in the genome of all domestic cats, sequences closely related to exogenous felv known as endogenous feline leukemia virus (enfelv), are present. enfelv are incapable of giving rise to infectious virus particles. however, transcription and translation of enfelv have been demonstrated in tissues of health ... | 2008 | 18295344 |
| virological survey in free-ranging wildcats (felis silvestris) and feral domestic cats in portugal. | to determine the presence of viral pathogens in natural areas a survey was conducted on an opportunistic sample of fifty eight wild (felis silvestris silvestris) and feral cats (f. s. catus). the biological materials included serum, lung tissue extract and stool. feline leukemia virus p27 antigen was detected in 13/50 serum/lung tissue extract samples (26%), canine distemper virus antibodies were detected in 2/26 serum/lung tissue extract samples (7.7%), feline coronavirus rna was present in 6/2 ... | 2012 | 22424865 |
| annotated features of domestic cat - felis catus genome. | domestic cats enjoy an extensive veterinary medical surveillance which has described nearly 250 genetic diseases analogous to human disorders. feline infectious agents offer powerful natural models of deadly human diseases, which include feline immunodeficiency virus, feline sarcoma virus and feline leukemia virus. a rich veterinary literature of feline disease pathogenesis and the demonstration of a highly conserved ancestral mammal genome organization make the cat genome annotation a highly in ... | 2014 | 25143822 |
| quantification and molecular characterization of the feline leukemia virus a receptor. | virus receptors and their expression patterns on the cell surface determine the cell tropism of the virus, host susceptibility and the pathogenesis of the infection. feline thiamine transport protein 1 (fthtr1) has been identified as the receptor for feline leukemia virus (felv) a. the goal of the present study was to develop a quantitative, taqman real-time pcr assay to investigate fthtr1 mrna expression in tissues of uninfected and felv-infected cats, cats of different ages, in tumor tissues a ... | 2011 | 21889617 |
| copy number polymorphism of endogenous feline leukemia virus-like sequences. | in the cat genome, endogenous feline leukemia virus (enfelv) exists as multiple, nearly full-length proviral sequences. even though no infectious virus is produced from enfelv sequences, transcription and translation have been demonstrated in tissues of healthy cats and in feline cell lines. to test the hypothesis that the enfelv loads play a role in exogenous felv-a infection and pathogenesis, we designed three real-time pcr assays to quantify u3 and env enfelv loads (two within u3 amplifying d ... | 2007 | 17329079 |
| worldwide occurrence of feline hemoplasma infections in wild felid species. | while hemoplasma infections in domestic cats are well studied, almost no information is available on their occurrence in wild felids. the aims of the present study were to investigate wild felid species as possible reservoirs of feline hemoplasmas and the molecular characterization of the hemoplasma isolates. blood samples from the following 257 wild felids were analyzed: 35 iberian lynxes from spain, 36 eurasian lynxes from switzerland, 31 european wildcats from france, 45 lions from tanzania, ... | 2007 | 17301277 |
| some viral and protozool diseases in the european wildcat (felis silvestris). | ten european wildcats (felis silvestris) were examined at necropsy and an additional 23 were examined clinically for evidence of viral diseases in scotland. two plasma samples taken from live free-living wildcats showed positive elisa reactions to feline leukemia antigen. a feline leukemia virus of subgroup a was isolated from one of these samples, taken from a wildcat in north-western scotland. no antibodies to feline coronavirus or feline immunodeficiency virus were detected in any sample. thr ... | 1991 | 1758037 |