| dopamine receptor antagonists as new mode-of-action insecticide leads for control of aedes and culex mosquito vectors. | new mode-of-action insecticides are sought to provide continued control of pesticide resistant arthropod vectors of neglected tropical diseases (ntds). we previously identified antagonists of the aadop2 d1-like dopamine receptor (dar) from the yellow fever mosquito, aedes aegypti, with toxicity to ae. aegypti larvae as leads for novel insecticides. to extend dar-based insecticide discovery, we evaluated the molecular and pharmacological characteristics of an orthologous dar target, cqdop2, from ... | 2015 | 25793586 |
| ongoing activity of toscana virus genotype a and west nile virus lineage 1 strains in turkey: a clinical and field survey. | toscana virus (tosv), west nile virus (wnv) and tickborne encephalitis virus (tbev) are among major viral pathogens causing febrile disease and meningitis/encephalitis. the impact of these viruses was investigated at a referral centre in ankara province, central anatolia in 2012, where previous reports suggested virus circulation but with scarce information on clinical cases and vector activity. serum and/or cerebrospinal fluid samples from 94 individuals were evaluated, in addition to field-col ... | 2014 | 25285941 |