| nairovirus rna sequences expressed by a semliki forest virus replicon induce rna interference in tick cells. | we report the successful infection of the cell line ise6 derived from ixodes scapularis tick embryos by the tick-borne hazara virus (hazv), a nairovirus in the family bunyaviridae. using a recombinant semliki forest alphavirus replicon that replicates in these cells, we were able to inhibit replication of hazv, and we showed that this blockage is mediated by the replication of the semliki forest alphavirus replicon; the vector containing the hazv nucleoprotein gene in sense or antisense orientat ... | 2005 | 15994788 |