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virucidal activity of haemaphysalis longicornis longicin p4 peptide against tick-borne encephalitis virus surrogate langat virus.longicin is a defensin-like peptide, identified from the midgut epithelium of hard tick haemaphysalis longicornis. several studies have already shown the antimicrobial and parasiticidal activities of longicin peptide and one of its synthetic partial analogs, longicin p4. in this study, longicin peptides were tested for potential antiviral activity against langat virus (lgtv), a tick-borne flavivirus.201626830840
synchronous langat virus infection of haemaphysalis longicornis using anal pore microinjection.the tick-borne encephalitis virus (tbev) serocomplex of flaviviruses consists of arboviruses that cause important diseases in animals and humans. the transmission of this group of viruses is commonly associated with tick species such as ixodes spp., dermacentor spp., and hyalomma spp. in the case of haemaphysalis longicornis, the detection and isolation of flaviviruses have been previously reported. however, studies showing survival dynamics of any tick-borne flavivirus in h. longicornis are sti ...201728714929
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