| orthologues of the drosophila melanogaster e75 molting control gene in the filarial parasites brugia malayi and dirofilaria immitis. | filarial parasites cause debilitating diseases in humans and domesticated animals. brugia malayi and dirofilaria immitis are transmitted by mosquitoes and infect humans and dogs, respectively. their life cycle is punctuated by a series of cuticular molts as they move between different hosts and tissues. an understanding of the genetic basis for these developmental transitions may suggest potential targets for vaccines or chemotherapeutics. nuclear receptor (nr) proteins have been implicated in m ... | 2008 | 17942167 |