| ring structure amino acids affect the suppressor activity of melon aphid-borne yellows virus p0 protein. | melon aphid-borne yellows virus (mabyv) is a newly identified polerovirus occurring in china. here, we demonstrate that the mabyv encoded p0 (p0(ma)) protein is a strong suppressor of post-transcriptional gene silencing (ptgs) with activity comparable to tobacco etch virus (tev) hc-pro. in addition we have shown that the lp f-box motif present at the n-terminus of p0(ma) is required for suppressor activity. detailed mutational analyses on p0(ma) revealed that changing the conserved trp 212 with ... | 2010 | 20667575 |