| mosquito transmission of the rodent malaria parasite plasmodium chabaudi. | serial blood passage of plasmodium increases virulence, whilst mosquito transmission inherently regulates parasite virulence within the mammalian host. it is, therefore, imperative that all aspects of experimental malaria research are studied in the context of the complete plasmodium life cycle. | 2012 | 23217144 |
| plasmodium chabaudi chabaudi malaria parasites can develop stable resistance to atovaquone with a mutation in the cytochrome b gene. | plasmodium falciparum, has developed resistance to many of the drugs in use. the recommended treatment policy is now to use drug combinations. the atovaquone-proguanil (ap) drug combination, is one of the treatment and prophylaxis options. atovaquone (atq) exerts its action by inhibiting plasmodial mitochondria electron transport at the level of the cytochrome bc1 complex. plasmodium falciparum in vitro resistance to atq has been associated with specific point mutations in the region spanning co ... | 2010 | 20492669 |
| cytokine responses of cd4+ t cells during a plasmodium chabaudi chabaudi (er) blood-stage infection in mice initiated by the natural route of infection. | investigation of host responses to blood stages of plasmodium spp, and the immunopathology associated with this phase of the life cycle are often performed on mice infected directly with infected red blood cells. thus, the effects of mosquito bites and the pre-erythrocytic stages of the parasite, which would be present in natural infection, are ignored in this paper, plasmodium chabaudi chabaudi infections of mice injected directly with infected red blood cells were compared with those of mice i ... | 2007 | 17555592 |