| small- and large-plaque variants of chikungunya virus in two vertebrate and seven invertebrate cell lines. | nine cells lines--bhk-21, vero, aedes albopictus, a. aegypti (monolayer and howwow vesicles), a. w-albus, a. vittatus, anopheles stephensi and culex quinquefasciatus--were infected with small- and large-plaque (sp, lp) variants of chikungunya virus. ross strain, and incubated at different temperatures. in the aedes (29 plus or minus 1 degrees c) and the vertebrate cell lines (36 degrees c), infectivity titers of extracellular virus rapidly reached a peak; cytopathic effect (cpe) occurred only in ... | 1975 | 235192 |