| [observation on the susceptibility of anopheles dirus to plasmodium yoelii yoelii]. | | 1985 | 4053316 |
| selection of anopheles dirus for refractoriness and susceptibility to plasmodium yoelii nigeriensis. | two lines of the oriental malaria vector mosquito anopheles dirus species a (diptera: culicidae), one fully refractory and one fully susceptible to plasmodium yoelii nigeriensis (an african rodent malaria parasite), were established after 17 generations of mass selection, followed by single female selection for one or two generations. prior to selection, the stock colony of an. dirus was 17% refractory. both lines of an. dirus produced abundant ookinetes that started to invade the midgut within ... | 1999 | 10608223 |
| trypsin and aminopeptidase activities in blood-fed females anopheles dirus (diptera: culicidae) of differing susceptibility to plasmodium yoelii nigeriensis. | midgut proteolytic enzymes contribute to the success or failure of plasmodium infection of the mosquito. the present study investigated trypsin and aminopeptidase activities in the midgut of two strains of anopheles dirus selected for susceptibility and refractoriness to plasmodium yoelii nigeriensis. at intervals of 6 hours following a bloodmeal, the midguts of fully engorged female mosquitos were dissected, homogenized, and assayed for enzyme activity. no differences trypsin activity (nmole/mi ... | 2002 | 12757211 |
| [study on the relationship between intracellular free calcium and melanization in oocysts of plasmodium yoelii]. | to study the change of intracellular free ca2+ in the oocyst when it melanized and to find out the relationship between the melanized oocyst and its intracellular level of free ca2+ in a plasmodium-refractory strain of anopheles dirus. | 2003 | 12884616 |
| [the internal control role of ribosomal protein s7 in the defense of anopheles dirus against plasmodium infection]. | to investigate the role of ribosomal protein s7 (rps7) in the defense of anopheles dirus against infection. | 2003 | 15108511 |
| two serine proteases from anopheles dirus haemocytes exhibit changes in transcript abundance after infection of an incompatible rodent malaria parasite, plasmodium yoelii. | serine proteases are involved in regulation of innate immune responses, such as haemolymph coagulation, melanization reaction and antimicrobial peptide synthesis. although several serine proteases have been characterized in anopheles gambiae (a. gambiae), few were cloned from other malaria vectors. in this study, we identified three cdna fragments of serine proteases (adsp1, adsp2 and adsp3) from haemocytes of an oriental malaria vector, anopheles dirus (a. dirus), by cloning of fragments amplif ... | 2006 | 16567047 |
| plasmodium yoelii: contribution of oocysts melanization to natural refractoriness in anopheles dirus. | it is well known that anopheles dirus is naturally refractory to rodent malaria parasite, plasmodium yoelii, but the mechanism is still largely unknown. here, we found that some p. yoelii taken into an. dirus could develop into oocysts, but oocysts were partially melanized at 7 days and completely melanized at 15 days post-infectious blood meal. transmission electronic microscopy could find the melanized p. yoelii oocysts in an. dirus as early as 5 days post-infection, with a few haemocytes atta ... | 2007 | 17416360 |
| involvement of prophenoloxidases in the suppression of plasmodium yoelii development by anopheles dirus. | anopheles dirus is refractory to a rodent malaria parasite, plasmodium yoelii, and melanized oocysts are manifested in infected mosquitoes. prophenoloxidase (ppo) is a zymogen whose active form mediates melanotic encapsulation of invading pathogens in mosquitoes. in this study, we cloned cdna fragments of four an. dirus ppos, that are orthologs of anopheles gambiae ppo2, ppo4, ppo5 and ppo6. adppo4 expression in hemocytes was induced in response to p. yoelii infection. rna interference using dou ... | 2009 | 19540233 |
| [function of tep1 gene during plasmodium yoelii infection in anopheles dirus]. | to study the role of tep1 gene from anopheles dirns during plasmodium yoelii infection by rna interference. | 2011 | 21823319 |
| ability of tep1 in intestinal flora to modulate natural resistance of anopheles dirus. | blocking transmission of malaria is a reliable way to control and eliminate infection. however, in-depth knowledge of the interaction between plasmodium and mosquito is needed. studies suggest that innate immunity is the main mechanism inhibiting development of malaria parasites in the mosquito. recent studies have found that use of antibiotics that inhibit the mosquito gut flora can reduce the immune response of anopheles gambiae, thereby contributing to the development of malaria parasites. in ... | 2013 | 23648664 |