| preliminary observations on the experimental transmission of scrapie to elk (cervus elaphus nelsoni) by intracerebral inoculation. | to determine the transmissibility of scrapie to rocky mountain elk (cervus elaphus nelsoni), six elk calves were inoculated intracerebrally with brain suspension from sheep naturally affected with scrapie. one elk developed a brain abscess and was euthanatized at 7 weeks postinoculation (pi), and two others died at 6 and 15 months pi because of physical injuries. at 25 and 35 months pi, two other elk died after brief terminal neurologic episodes. necropsy of these revealed moderate weight loss b ... | 2003 | 12627716 |
| transmission of sheep scrapie to elk (cervus elaphus nelsoni) by intracerebral inoculation: final outcome of the experiment. | this is a final report of an experimental transmission of sheep scrapie agent by intracerebral inoculation to rocky mountain elk (cervus elaphus nelsoni). it documents results obtained in experimental (n = 6) and control (n = 2) elk. during the first 2 years postinoculation (pi), 3 animals died or were euthanized because of infection or injuries other than spongiform encephalopathy (se). in years 3 and 4 pi, 3 other inoculated elk died after brief terminal neurological episodes. necropsy of thes ... | 2004 | 15305743 |