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genetic variability of the coding region for the prion protein gene (prnp) in gayal (bos frontalis).the gayal (bos frontalis) is a rare semi-wild bovid species in which bovine spongiform encephalopathy (bse) has not been reported. polymorphisms of the prion protein gene (prnp) have been correlated significantly with resistance to bse. in this study, the coding region of prnp was cloned and characterized in samples from 125 gayal. a total of ten single nucleotide polymorphisms (snps), including six silent mutations (c60t, g75a, a108t, g126a, c357t and c678t) and four mis-sense mutations (c8a, g ...201121633886
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