| antivenomics of atropoides mexicanus and atropoides picadoi snake venoms: relationship to the neutralization of toxic and enzymatic activities. | viperid snakes of the genus atropoides are distributed in mexico and central america and, owing to their size and venom yield, are capable of provoking severe envenomings in humans. this study evaluated, using an 'antivenomics' approach, the ability of a polyspecific (polyvalent) antivenom manufactured in costa rica to recognize the proteins of atropoides mexicanus and a. picadoi venoms, which are not included in the immunization mixture. in addition, the neutralization of lethal, hemorrhagic, m ... | 2010 | 21544177 |
| contributions of the snake venoms of bothrops asper, crotalus simus and lachesis stenophrys to the paraspecificity of the central american polyspecific antivenom (polival-icp). | polival-icp antivenom is produced from plasma of horses immunized toward the venoms of bothrops asper, crotalus simus and lachesis stenophrys. the antibody response induced by these venoms confers polival-icp the capacity to neutralize the venoms of the most important central american viperids, including not only homologous venoms (i.e., venoms used as immunogen), but many heterologous venoms (i.e., venoms not used as immunogen). in this work, the individual contributions of homologous venoms to ... | 2018 | 29407870 |
| isolation and characterization of four medium-size disintegrins from the venoms of central american viperid snakes of the genera atropoides, bothrops, cerrophidion and crotalus. | four disintegrins were isolated from the venoms of the central american viperid snakes atropoides mexicanus (atropoimin), bothrops asper (bothrasperin), cerrophidion sasai (sasaimin), and crotalus simus (simusmin). purifications were performed by reverse-phase hplc. the four disintegrins have biochemical characteristics, i.e. molecular mass and location of cys, which allow their classification within the group of medium-size disintegrins. all of them present the canonical rgd sequence, which det ... | 2014 | 25457103 |