| neutralization of bothrops mattogrossensis snake venom from bolivia: experimental evaluation of llama and donkey antivenoms produced by caprylic acid precipitation. | polyspecific bothropic/crotalic and bothropic/lachesic antivenoms were produced in bolivia by immunizing two donkeys with the venoms of bothrops mattogrossensis and crotalus durissus terrificus and one llama with the venoms of b. mattogrossensis and lachesis muta. these antivenoms are currently being used for snakebite envenomation in bolivia. the rationale for using these animals is that donkeys and llamas are better adapted than horses to the high altitudes in south america and constitute good ... | 2010 | 19647761 |
| purification and biochemical characterization of three myotoxins from bothrops mattogrossensis snake venom with toxicity against leishmania and tumor cells. | bothrops mattogrossensis snake is widely distributed throughout eastern south america and is responsible for snakebites in this region. this paper reports the purification and biochemical characterization of three new phospholipases a2 (pla2s), one of which is presumably an enzymatically active asp49 and two are very likely enzymatically inactive lys49 pla2 homologues. the purification was obtained after two chromatographic steps on ion exchange and reverse phase column. the 2d sds-page analysis ... | 2014 | 24724078 |
| a new species of bothrops (serpentes: viperidae: crotalinae) from pampas del heath, southeastern peru, with comments on the systematics of the bothrops neuwiedi species group. | we describe a new species of pitviper of the genus bothrops from the peruvian pampas del heath, in the bahuaja-sonene national park. pampas del heath is an area of seasonally flooded savannas and a northwestern extension of the gran chaco boliviano-paraguayo. the new species is easily distinguished from its congeners by the exclusive combination of dorsal color pattern of body consisting of small c-shaped blotches, postocular stripe originating posteriorly to the eye, covering posterior supralab ... | 2019 | 31716461 |
| isolation, biochemical characterization and antiparasitic activity of bmattx-iv, a basic lys49-phospholipase a2 from the venom of bothrops mattogrossensis from paraguay. | functional and structural diversity of proteins of snake venoms is coupled with a wide repertoire of pharmacological effects. snake venoms are targets of studies linked to searching molecules with biotechnological potential. | 2019 | 31340737 |
| tabebuia aurea decreases hyperalgesia and neuronal injury induced by snake venom. | tabebuia aurea (silva manso) benth. & hook. f. ex s. moore is used as anti-inflammatory, analgesic and antiophidic in traditional medicine, though its pharmacological proprieties are still underexplored. in the bothropic envenoming, pain is a key symptom drove by an intense local inflammatory and neurotoxic event. the antivenom serum therapy is still the main treatment despite its poor local effects against pain and tissue injury. furthermore, it is limited to ambulatorial niches, giving space f ... | 2019 | 30590196 |