Publications

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non-invasive monitoring of glucocorticoid metabolites in banded mongooses (mungos mungo) in response to physiological and biological challenges.free-ranging banded mongooses are infected by the novel pathogen, mycobacterium mungi in northern botswana. a reliable method for determining stress-related physiological responses in banded mongooses will increase our understanding of the stress response in m. mungi infection. therefore, our aim was to examine the suitability of four enzyme immunoassays (eias) for monitoring adrenocortical endocrine function in captive and free-ranging banded mongooses based on fecal glucocorticoid metabolite ( ...201222926328
the impact of health status on dispersal behavior in banded mongooses (mungos mungo).while disease and injury have obvious impacts on mortality, they can have less understood non-lethal impacts on behavior. these behavioral effects might have a significant consequences for population-level disease dynamics if diseased individuals are more or less likely to disperse. we opportunistically observed dispersal events in banded mongooses (mungos mungo) that were either healthy or unhealthy due to injury and/or clinical signs of a novel tuberculosis pathogen, mycobacterium mungi. we fo ...201424504905
animal-adapted members of the mycobacterium tuberculosis complex endemic to the southern african subregion.members of the mycobacterium tuberculosis complex (mtc) cause tuberculosis (tb) in both animals and humans. in this article, three animal-adapted mtc strains that are endemic to the southern african subregion - that is, mycobacterium suricattae, mycobacterium mungi, and the dassie bacillus - are reviewed with a focus on clinical and pathological presentations, geographic distribution, genotyping methods, diagnostic tools and evolution. moreover, factors influencing the transmission and establish ...201627246904
draft genome sequence of the mycobacterium tuberculosis complex pathogen m. mungi, identified in a banded mongoose (mungos mungo) in northern botswana.mycobacterium mungi, a mycobacterium tuberculosis complex pathogen, has emerged in banded mongoose in northern botswana and northwest zimbabwe. the pathogen is transmitted through infected secretions used in olfactory communication behavior (k. a. alexander, c. e. sanderson, m. h. larsen, s. robbe-austerman, m. c. williams, and m. v. palmer, mbio 7(3):e00281-16, 2016, http://dx.doi.org/10.1128/mbio.00281-16). we announce here the draft genome sequence of this emerging pathogen.201627469947
whole genome sequence analysis of mycobacterium suricattae.tuberculosis occurs in various mammalian hosts and is caused by a range of different lineages of the mycobacterium tuberculosis complex (mtbc). a recently described member, mycobacterium suricattae, causes tuberculosis in meerkats (suricata suricatta) in southern africa and preliminary genetic analysis showed this organism to be closely related to an mtbc pathogen of rock hyraxes (procavia capensis), the dassie bacillus. here we make use of whole genome sequencing to describe the evolution of th ...201526542221
pathology of the emerging mycobacterium tuberculosis complex pathogen, mycobacterium mungi, in the banded mongoose ( mungos mungo).wild banded mongooses ( mungos mungo) in northeastern botswana and northwest zimbabwe are infected with a novel mycobacterium tuberculosis complex (mtc) pathogen, mycobacterium mungi. we evaluated gross and histologic lesions in 62 infected mongooses (1999-2017). many tissues contained multifocal irregular, lymphohistiocytic to granulomatous infiltrates and/or multifocal or coalescing noncaseating to caseating granulomas with variable numbers of intralesional acid-fast bacilli. over one-third of ...201729258402
animal-adapted members of the <i>mycobacterium tuberculosis</i> complex endemic to the southern african subregion.members of the mycobacterium tuberculosis complex (mtc) cause tuberculosis (tb) in both animals and humans. in this article, three animal-adapted mtc strains that are endemic to the southern african subregion - that is, mycobacterium suricattae, mycobacterium mungi, and the dassie bacillus - are reviewed with a focus on clinical and pathological presentations, geographic distribution, genotyping methods, diagnostic tools and evolution. moreover, factors influencing the transmission and establish ...201627796109
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