| feral swine virome is dominated by single-stranded dna viruses and contains a novel orthopneumovirus which circulates both in feral and domestic swine. | feral swine are known reservoirs for various pathogens that can adversely affect domestic animals. to assess the viral ecology of feral swine in the usa, metagenomic sequencing was performed on 100 pooled nasal swabs. the virome was dominated by small, ssdna viruses belonging to the families circoviridae, anelloviridae and parvovirinae. only four rna viruses were identified: porcine kobuvirus, porcine sapelovirus, atypical porcine pestivirus and a novel orthopneumovirus, provisionally named swin ... | 2016 | 27417702 |
| new and emerging pathogens in canine infectious respiratory disease. | canine infectious respiratory disease is a common, worldwide disease syndrome of multifactorial etiology. this review presents a summary of 6 viruses (canine respiratory coronavirus, canine pneumovirus, canine influenza virus, pantropic canine coronavirus, canine bocavirus, and canine hepacivirus) and 2 bacteria (streptococcus zooepidemicus and mycoplasma cynos) that have been associated with respiratory disease in dogs. for some pathogens a causal role is clear, whereas for others, ongoing rese ... | 2014 | 24232191 |
| molecular surveillance of traditional and emerging pathogens associated with canine infectious respiratory disease. | a molecular survey for traditional and emerging pathogens associated with canine infectious respiratory disease (cird) was conducted in italy between 2011 and 2013 on a total of 138 dogs, including 78 early acute clinically ill cird animals, 22 non-clinical but exposed to clinically ill cird dogs and 38 cird convalescent dogs. the results showed that canine parainfluenza virus (cpiv) was the most commonly detected cird pathogen, followed by canine respiratory coronavirus (crcov), bordetella bron ... | 2016 | 27527760 |
| co-infections with respiratory viruses in dogs with bacterial pneumonia. | bacterial pneumonia (bp) is an inflammation of the lower airways and lung parenchyma secondary to bacterial infection. the pathogenesis of bp in dogs is complex and the role of canine respiratory viruses has not been fully evaluated. | 2015 | 25818209 |
| canine pneumovirus replicates in mouse lung tissue and elicits inflammatory pathology. | canine pneumovirus (cnpnv) was recently isolated from the respiratory tracts of shelter dogs and shares sequence similarity with the rodent pathogen, pneumonia virus of mice (pvm). we show here that cnpnv replicates in and can elicit local proinflammatory cytokine production and neutrophil recruitment to lung tissue and the airways. in contrast to pvm j3666 infection, fatal cnpnv infections are observed only in response to high titer intranasal inocula (>67 tcid(50) units). sera from mice that r ... | 2011 | 21600624 |
| genomic analysis of a pneumovirus isolated from dogs with acute respiratory disease. | a previously unrecognized virus belonging to the subfamily pneumovirinae and most closely related to murine pneumovirus (mpv) was identified in domestic dogs in 2 related animal shelters. additional diagnostic testing yielded 3 new viral isolates and identified 6 additional pcr positive dogs from other usa locations indicating that its distribution is not geographically limited. nucleotide sequences encompassing 9 of the 10 genes were compared to the only 2 available mpv strains, 15 and j3666. s ... | 2011 | 21324612 |
| detection of canine pneumovirus in dogs with canine infectious respiratory disease. | canine pneumovirus (cnpnv) was recently identified during a retrospective survey of kenneled dogs in the united states. in this study, archived samples from pet and kenneled dogs in the united kingdom were screened for cnpnv to explore the relationship between exposure to cnpnv and the development of canine infectious respiratory disease (cird). within the pet dog population, cnpnv-seropositive dogs were detected throughout the united kingdom and republic of ireland, with an overall estimated se ... | 2013 | 24088858 |
| full-genome analysis of a canine pneumovirus causing acute respiratory disease in dogs, italy. | an outbreak of canine infectious respiratory disease (cird) associated to canine pneumovirus (cnpnv) infection is reported. the outbreak occurred in a shelter of the apulia region and involved 37 out of 350 dogs that displayed cough and/or nasal discharge with no evidence of fever. the full-genomic characterisation showed that the causative agent (strain bari/100-12) was closely related to cnpnvs that have been recently isolated in the usa, as well as to murine pneumovirus, which is responsible ... | 2014 | 24400129 |
| european surveillance of emerging pathogens associated with canine infectious respiratory disease. | canine infectious respiratory disease (cird) is a major cause of morbidity in dogs worldwide, and is associated with a number of new and emerging pathogens. in a large multi-centre european study the prevalences of four key emerging cird pathogens; canine respiratory coronavirus (crcov), canine pneumovirus (cnpnv), influenza a, and mycoplasma cynos (m. cynos); were estimated, and risk factors for exposure, infection and clinical disease were investigated. cird affected 66% (381/572) of the dogs ... | 2017 | 29173585 |