relative in vitro rates of attachment and penetration of hydrogel soft contact lenses by haplotypes of investigate the relative abilities of different haplotypes of the fusarium solani (fssc)-fusarium oxysporum (fosc) complexes to attach to and invade hydrogel contact lenses.200919411965
multidrug-resistant fusarium in keratitis: a clinico-mycological study of keratitis infections in chennai, this study, we aimed to present the first molecular epidemiological data from chennai, india, analyse keratitis cases that have been monitored in a university hospital during 2 years, identify the responsible fusarium species and determine antifungal susceptibilities. a total of 10 cases of keratitis were included in the study. fusarium isolates were identified using the second largest subunit of the rna polymerase gene (rpb2) and the translation elongation factor 1 alpha (tef1). antifungal s ...201727766684
veterinary fusarioses within the united states.multilocus dna sequence data were used to assess the genetic diversity and evolutionary relationships of 67 fusarium strains from veterinary sources, most of which were from the united states. molecular phylogenetic analyses revealed that the strains comprised 23 phylogenetically distinct species, all but two of which were previously known to infect humans, distributed among eight species complexes. the majority of the veterinary isolates (47/67 = 70.1%) were nested within the fusarium solani sp ...201627605713
morphological and phylogenetic analysis of fusarium solani species complex in malaysia.members of fusarium solani species complex (fssc) have been known as plant, animal, and human pathogens. nevertheless, the taxonomic status of such an important group of fungi is still very confusing and many new species as well as lineages have been elucidated recently. unfortunately, most of the new taxa came from temperate and subtropical regions. therefore, the objectives of the present study were to identify strains of fssc recovered from different sources in malaysia. in the present study, ...201525238930
global distribution of two fungal pathogens threatening endangered sea turtles.nascent fungal infections are currently considered as one of the main threats for biodiversity and ecosystem health, and have driven several animal species into critical risk of extinction. sea turtles are one of the most endangered groups of animals and only seven species have survived to date. here, we described two pathogenic species, i.e., fusarium falciforme and fusarium keratoplasticum, that are globally distributed in major turtle nesting areas for six sea turtle species and that are impl ...201424465748
molecular analyses of fusarium isolates recovered from a cluster of invasive mold infections in a brazilian hospital.invasive fusariosis (if) is a rare but often fatal fungal infection in immunosuppressed patients. in 2007, cases of if above the expected epidemiologic baseline were detected in the hematology ward of a hospital in rio de janeiro, brazil. possible sources of infection were investigated by performing environmental sampling and patient isolate collection, followed by molecular typing. isolates from dermatology patients with superficial fusariosis were included in the study for comparison to molecu ...201323363475
comparison of dna microarray, loop-mediated isothermal amplification (lamp) and real-time pcr with dna sequencing for identification of fusarium spp. obtained from patients with hematologic malignancies.the performance of three molecular biology techniques, i.e., dna microarray, loop-mediated isothermal amplification (lamp), and real-time pcr were compared with dna sequencing for properly identification of 20 isolates of fusarium spp. obtained from blood stream as etiologic agent of invasive infections in patients with hematologic malignancies. dna microarray, lamp and real-time pcr identified 16 (80%) out of 20 samples as fusarium solani species complex (fssc) and four (20%) as fusarium spp. t ...201728324245
disseminated fusariosis and hematologic malignancies, a still devastating association. report of three new cases.fungi of the genus fusarium are primarily plant pathogens and saprobes that produce disseminated infections in immunologically deficient humans. after aspergillosis, disseminated fusariosis is the second most common cause of invasive infection by filamentous fungi in patients with hematologic malignancies or those undergoing transplants of hematopoietic progenitors.201525936697
epidemiological study of fusarium species causing invasive and superficial fusariosis in japan, fusarium species are known etiological agents of human fungal infection; however, there has been no report of a large-scale epidemiological study on the etiological agents of fusariosis. a total of 73 fusarium isolates from patients with invasive fusariosis (if, n= 36) or superficial fusariosis (sf, n= 37), which were obtained at hospitals located in 28 prefectures in japan between 1998 and 2015, were used for this study. fusarium isolates were identified using fusarium- and fusarium s ...201728250364
molecular and pathological characterization of fusarium solani species complex infection in the head and lateral line system of sphyrna lewini.a severe fungal infection affecting the head and lateral line system was diagnosed in 7 captive scalloped hammerhead sharks sphyrna lewini in an aquarium in thailand. extensive and severe necrotizing cellulitis was consistently observed microscopically along the cephalic and lateral line canals in conjunction with positive fungal cultures for fusarium sp. molecular phylogenetic analysis was performed from 3 isolates based on the nucleotide sequences containing internally transcribed spacer (its) ...201627503915
fatal fusarium solani species complex infections in elasmobranchs: the first case report for black spotted stingray (taeniura melanopsila) and a literature review.fusarium species are environmental saprophytic fungi. among the many fusarium species, members of the fusarium solani species complex (fssc) are the most prevalent and virulent in causing human and animal infections. in this study, we describe the first case of fatal fssc infection in a black spotted stingray and three concomitant infections in scalloped hammerhead sharks. in the stingray, cutaneous lesions were characterised by ulcers and haemorrhage of the ventral pectoral fin, or 'ray', espec ...201526095191
phylogenetic relationships among members of the fusarium solani species complex in human infections and the descriptions of f. keratoplasticum sp. nov. and f. petroliphilum stat. nov.fusarium species are frequently associated with mycotic keratitis and, to a lesser extent, cases of localized and disseminated infections. the fusarium solani species complex (fssc) is the most common group of fusaria associated with human infectious diseases. several studies to date have revealed dozens of strongly supported phylogenetic species within this important evolutionary clade, though little work has been done to improve the taxonomy and understanding of the reproductive mode and pheno ...201323396261
an endohyphal bacterium (chitinophaga, bacteroidetes) alters carbon source use by fusarium keratoplasticum (f. solani species complex, nectriaceae).bacterial endosymbionts occur in diverse fungi, including members of many lineages of ascomycota that inhabit living plants. these endosymbiotic bacteria (endohyphal bacteria, ehb) often can be removed from living fungi by antibiotic treatment, providing an opportunity to assess their effects on functional traits of their fungal hosts. we examined the effects of an endohyphal bacterium (chitinophaga sp., bacteroidetes) on substrate use by its host, a seed-associated strain of the fungus fusarium ...201728382021
melanization of fusarium keratoplasticum (f. solani species complex) during disseminated fusariosis in a patient with acute leukemia.fusarium spp. are recognized as the second most frequently filamentous fungi causing opportunistic infections and particularly important due to the increasing number of immunocompromised patients. f. keratoplasticum (a member of f. solani species complex) is one of the fusarium species commonly associated with human infection, and therefore, studies on the virulence of this fungus are needed. this study aimed to confirm the presence of melanin in f. keratoplasticum from a patient with systemic f ...201728616680
biofilm formation and resistance to fungicides in clinically relevant members of the fungal genus fusarium.clinically relevant members of the fungal genus, fusarium, exhibit an extraordinary genetic diversity and cause a wide spectrum of infections in both healthy individuals and immunocompromised patients. generally, fusarium species are intrinsically resistant to all systemic antifungals. we investigated whether the presence or absence of the ability to produce biofilms across and within fusarium species complexes is linked to higher resistance against antifungals. a collection of 41 fusarium strai ...201829371509
rose bengal photodynamic antimicrobial therapy: a novel treatment for resistant fusarium evaluate the efficacy of rose bengal pdat for the management of a patient with multidrug-resistant fusarium keratoplasticum keratitis unresponsive to standard clinical treatment.201728691942
clonality, recombination, and hybridization in the plumbing-inhabiting human pathogen fusarium keratoplasticum inferred from multilocus sequence typing.recent work has shown that fusarium species and genotypes most commonly associated with human infections, particularly of the cornea (mycotic keratitis), are the same as those most commonly isolated from plumbing systems. the species most dominant in plumbing biofilms is fusarium keratoplasticum, a cosmopolitan fungus known almost exclusively from animal infections and biofilms. to better understand its diversity and population dynamics, we developed and utilized a nine-locus sequence-based typi ...201424766947
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