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identification of the lipodepsipeptide mdn-0066, a novel inhibitor of vhl/hif pathway produced by a new pseudomonas species.throughout recent history, metabolites of microbial origin have had an extraordinary impact on the welfare of humanity. in fact, natural products have largely been--and still are--considered an exceedingly valuable platform for the discovery of new drugs against diverse pathologies. such value is partly due to their higher complexity and chemical diversity as compared to those of synthetic and combinatorial compounds. mutations in the von hippel-lindau (vhl) gene are responsible for vhl disease, ...201526018559
characterization of antimicrobial-producing beneficial bacteria isolated from huanglongbing escape citrus trees.the microbiome associated with crop plants has a strong impact on their health and productivity. candidatus liberibacter asiaticus (las), the bacterial pathogen responsible for huanglongbing (hlb) disease, lives inside the phloem of citrus plants including the root system. it has been suggested that las negatively affects citrus microbiome. on the other hand, members of citrus microbiome also influence the interaction between las and citrus. here, we report the isolation and characterization of ...201729375487
pseudomonas kribbensis sp. nov., isolated from garden soils in daejeon, korea.two bacterial strains, 46-1 and 46-2(t), were isolated from garden soil. these strains were observed to be aerobic, gram-stain negative, rod-shaped, non-spore-forming, motile and catalase and oxidase positive. phylogenetic analysis based on 16s rrna gene sequences showed that the two strains shared 100 % sequence similarity with each other and belong to the genus pseudomonas in the class gammaproteobacteria. the concatenated 16s rrna, gyrb, rpob and rpod gene sequences further confirmed that the ...201627460204
pseudomonas granadensis sp. nov., a new bacterial species isolated from the tejeda, almijara and alhama natural park, granada, spain.during the course of screening bacterial isolates as sources of as-yet unknown bioactive compounds with pharmaceutical applications, a chemo-organotrophic, gram-negative bacterium was isolated from a soil sample taken from the tejeda, almijara and alhama natural park, granada, spain. strain f-278,770(t) was oxidase- and catalase-positive, aerobic, with a respiratory type of metabolism with oxygen as the terminal electron acceptor, non-spore-forming and motile by one polar flagellum, although som ...201525410940
pseudomonas turukhanskensis sp. nov., isolated from oil-contaminated soils.a bacterial strain named ib1.1t was isolated in a screening of hydrocarbon-degrading bacteria from oil-contaminated soils on the territory of the turukhansk district of krasnoyarsk krai, east siberia, russia. the 16s rrna gene sequence had 98.7 % identity with respect to the closest phylogenetic relative, pseudomonas granadensis f-278,770t, and the next most closely related species with 98.6 % similarity was pseudomonaspunonensis, suggesting that ib1.1t should be classified within the genus pseu ...201627503709
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