Publications

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coronavirus diversity, phylogeny and interspecies jumping.the sars epidemic has boosted interest in research on coronavirus biodiversity and genomics. before 2003, there were only 10 coronaviruses with complete genomes available. after the sars epidemic, up to december 2008, there was an addition of 16 coronaviruses with complete genomes sequenced. these include two human coronaviruses (human coronavirus nl63 and human coronavirus hku1), 10 other mammalian coronaviruses [bat sars coronavirus, bat coronavirus (bat-cov) hku2, bat-cov hku4, bat-cov hku5, ...200919546349
coronavirus genomics and bioinformatics analysis.the drastic increase in the number of coronaviruses discovered and coronavirus genomes being sequenced have given us an unprecedented opportunity to perform genomics and bioinformatics analysis on this family of viruses. coronaviruses possess the largest genomes (26.4 to 31.7 kb) among all known rna viruses, with g + c contents varying from 32% to 43%. variable numbers of small orfs are present between the various conserved genes (orf1ab, spike, envelope, membrane and nucleocapsid) and downstrea ...201021994708
discovery of seven novel mammalian and avian coronaviruses in the genus deltacoronavirus supports bat coronaviruses as the gene source of alphacoronavirus and betacoronavirus and avian coronaviruses as the gene source of gammacoronavirus and deltacoronavirus.recently, we reported the discovery of three novel coronaviruses, bulbul coronavirus hku11, thrush coronavirus hku12, and munia coronavirus hku13, which were identified as representatives of a novel genus, deltacoronavirus, in the subfamily coronavirinae. in this territory-wide molecular epidemiology study involving 3,137 mammals and 3,298 birds, we discovered seven additional novel deltacoronaviruses in pigs and birds, which we named porcine coronavirus hku15, white-eye coronavirus hku16, sparr ...201222278237
epidemiology and evolution of novel deltacoronaviruses in birds in central china.the variety and widespread of coronavirus in natural reservoir animals is likely to cause epidemics via interspecific transmission, which has attracted much attention due to frequent coronavirus epidemics in recent decades. birds are natural reservoir of various viruses, but the existence of coronaviruses in wild birds in central china has been barely studied. some bird coronaviruses belong to the genus of deltacoronavirus. to explore the diversity of bird deltacoronaviruses in central china, we ...202133559368
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