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novel thogotovirus associated with febrile illness and death, united states, 2014.a previously healthy man from eastern kansas, usa, sought medical care in late spring because of a history of tick bite, fever, and fatigue. the patient had thrombocytopenia and leukopenia and was given doxycycline for a presumed tickborne illness. his condition did not improve. multiorgan failure developed, and he died 11 days after illness onset from cardiopulmonary arrest. molecular and serologic testing results for known tickborne pathogens were negative. however, testing of a specimen for a ...025899080
surveillance for tick-borne viruses near the location of a fatal human case of bourbon virus (family orthomyxoviridae: genus thogotovirus) in eastern kansas, 2015.bourbon virus (family orthomyxoviridae: genus thogotovirus) was first isolated from a human case-patient residing in bourbon county, kansas, who subsequently died. before becoming ill in late spring of 2014, the patient reported several tick bites. in response, we initiated tick surveillance in bourbon county and adjacent southern linn county during spring and summer of 2015. we collected 20,639 host-seeking ticks representing four species from 12 sites. amblyomma americanum (l.) (acari: ixodida ...201829365128
bourbon virus in field-collected ticks, missouri, usa.bourbon virus (brbv) was first isolated in 2014 from a resident of bourbon county, kansas, usa, who died of the infection. in 2015, an ill payne county, oklahoma, resident tested positive for antibodies to brbv, before fully recovering. we retrospectively tested for brbv in 39,096 ticks from northwestern missouri, located 240 km from bourbon county, kansas. we detected brbv in 3 pools of amblyomma americanum (l.) ticks: 1 pool of male adults and 2 pools of nymphs. detection of brbv in a. america ...201729148395
bourbon virus: a novel pathogen. 201627008057
molecular, serological and in vitro culture-based characterization of bourbon virus, a newly described human pathogen of the genus thogotovirus.in june of 2014, a previously healthy man from kansas with a recent history of tick exposure died from complications related to an illness marked by fever, thrombocytopenia and leukopenia. an isolate was derived from the blood of this patient during the course of diagnostic testing. this isolate was subsequently identified as a novel orthomyxovirus of the genus thogotovirus by next generation sequencing and was named bourbon virus after the patient's county of residence.201526609638
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