| tofla virus: a newly identified nairovirus of the crimean-congo hemorrhagic fever group isolated from ticks in japan. | ixodid ticks transmit several important viral pathogens. we isolated a new virus (tofla virus: tflv) from heamaphysalis flava and heamaphysalis formsensis in japan. the full-genome sequences revealed that tflv belonged to the genus nairovirus, family bunyaviridae. phylogenetic analyses and neutralization tests suggested that tflv is closely related to the hazara virus and that it is classified into the crimean-congo hemorrhagic fever group. tflv caused lethal infection in ifnar ko mice. the tflv ... | 2016 | 26863911 |