| characterization of fitzroy river virus and serologic evidence of human and animal infection. | in northern western australia in 2011 and 2012, surveillance detected a novel arbovirus in mosquitoes. genetic and phenotypic analyses confirmed that the new flavivirus, named fitzroy river virus, is related to sepik virus and wesselsbron virus, in the yellow fever virus group. most (81%) isolates came from aedes normanensis mosquitoes, providing circumstantial evidence of the probable vector. in cell culture, fitzroy river virus replicated in mosquito (c6/36), mammalian (vero, psek, and bsr), a ... | 2017 | 28726621 |
| cortical neurons derived from equine induced pluripotent stem cells are susceptible to neurotropic flavivirus infection and replication: an in vitro model for equine neuropathic diseases. | horses are susceptible to a number of neurotropic viruses, including west nile virus (wnv), which is a pathogen of global significance in both horses and humans. however, there are no in vitro models with which to study infectious neuropathic diseases in the horse. in an effort to redress this we have generated neurons from equine induced pluripotent stem cells (equipscs) that express a range of cortical neuron-specific markers, in addition to the membrane-bound ligand ephrin b3, which plays an ... | 2018 | 29562867 |