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ground squirrel hepatitis virus (gshv) infection and hepatocellular carcinoma in the canadian richardson ground squirrel (spermophilus richardsonii).sera and livers from 40 richardson ground squirrels were examined for evidence of ground squirrel hepatitis virus (gshv) infection and hepatocellular carcinoma. twenty-five sera were obtained from fully grown adult ground squirrels and 15 from young ground squirrels estimated to be between 6-8 weeks of age. all animals had been caught in the wild and had spent less than 1 month in captivity. sixteen sera (40%) had at least one serologic marker of gshv (2 with gshv surface antigen, 3 gshv core an ...19863033421
hepatocellular carcinoma in richardson's ground squirrels (spermophilus richardsonii): evidence for association with hepatitis b-like virus infection.during studies of seasonal obesity, a high frequency of hepatic neoplasms was observed in richardson's ground squirrels. of 12 richardson's ground squirrels examined thoroughly, 7 had mild or moderate degrees of chronic portal hepatitis and 6 (50%) had hepatocellular carcinoma. serological tests for hepadnavirus surface antigen, anti-core antibody and virion dna that recognize the ground squirrel hepatitis virus of california ground squirrels (spermophilus beecheyi) were uniformly negative. sout ...19911646762
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