host and viral traits predict zoonotic spillover from mammals. | the majority of human emerging infectious diseases are zoonotic, with viruses that originate in wild mammals of particular concern (for example, hiv, ebola and sars). understanding patterns of viral diversity in wildlife and determinants of successful cross-species transmission, or spillover, are therefore key goals for pandemic surveillance programs. however, few analytical tools exist to identify which host species are likely to harbour the next human virus, or which viruses can cross species ... | 2017 | 28636590 |
ground squirrel hepatitis virus (gshv) infection and hepatocellular carcinoma in the canadian richardson ground squirrel (spermophilus richardsonii). | sera and livers from 40 richardson ground squirrels were examined for evidence of ground squirrel hepatitis virus (gshv) infection and hepatocellular carcinoma. twenty-five sera were obtained from fully grown adult ground squirrels and 15 from young ground squirrels estimated to be between 6-8 weeks of age. all animals had been caught in the wild and had spent less than 1 month in captivity. sixteen sera (40%) had at least one serologic marker of gshv (2 with gshv surface antigen, 3 gshv core an ... | 1986 | 3033421 |
hepatocellular carcinoma in richardson's ground squirrels (spermophilus richardsonii): evidence for association with hepatitis b-like virus infection. | during studies of seasonal obesity, a high frequency of hepatic neoplasms was observed in richardson's ground squirrels. of 12 richardson's ground squirrels examined thoroughly, 7 had mild or moderate degrees of chronic portal hepatitis and 6 (50%) had hepatocellular carcinoma. serological tests for hepadnavirus surface antigen, anti-core antibody and virion dna that recognize the ground squirrel hepatitis virus of california ground squirrels (spermophilus beecheyi) were uniformly negative. sout ... | 1991 | 1646762 |