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eight whole-genome assemblies of yersinia pestis subsp. microtus bv. caucasica isolated from the common vole (microtus arvalis) plague focus in dagestan, russia.we here report the draft genome sequences of 8 yersinia pestis subsp. microtus bv. caucasica strains isolated from the east caucasian (previous name, dagestan) mountain focus (no. 39), representing the most ancient branch of the 0.pe2 phylogroup circulating in populations of common voles (microtus arvalis).201728839028
virulence of ppst+ and ppst- strains of yersinia pestis for guinea-pigs.guinea-pigs were infected subcutaneously or by respiratory challenge with plasmid-containing (ppst+pcad+pfra+) yersinia pestis strain 358 and its ppst-pcad+pfra+, ppst+pcad+pfra- and ppst-pcad+pfra- derivatives, grown in vitro at 28 degrees c or at 37 degrees c. lack of plasmid ppst did not lead to an increase in ld50 with either route of challenge. when the virulence of the four y. pestis strains grown at the two temperatures was compared, the ld50 values of those grown at 37 degrees c were low ...19968958247
yersinia pestis caf1 protein: effect of sequence polymorphism on intrinsic disorder propensity, serological cross-reactivity and cross-protectivity of isoforms.yersinia pestis caf1 is a multifunctional protein responsible for antiphagocytic activity and is a key protective antigen. it is generally conserved between globally distributed y. pestis strains, but y. pestis subsp. microtus biovar caucasica strains circulating within populations of common voles in georgia and armenia were reported to carry a single substitution of alanine to serine. we investigated polymorphism of the caf1 sequences among other y. pestis subsp. microtus strains, which have a ...201627606595
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