| non-human primates in outdoor enclosures: risk for infection with rodent-borne hantaviruses. | different species of non-human primates have been exploited as animal disease models for human hantavirus infections. to study the potential risk of natural hantavirus infection of non-human primates, we investigated serum samples from non-human primates of three species living in outdoor enclosures of the german primate center (gpc), göttingen, located in a hantavirus endemic region of central germany. for that purpose we used serological assays based on recombinant antigens of the bank vole (m ... | 2011 | 20727685 |
| dampening of population cycles in voles affects small mammal community structure, decreases diversity, and increases prevalence of a zoonotic disease. | long-term decline and depression of density in cyclic small rodents is a recent widespread phenomenon. these observed changes at the population level might have cascading effects at the ecosystem level. here, we assessed relationships between changing boreal landscapes and biodiversity changes of small mammal communities. we also inferred potential effects of observed community changes for increased transmission risk of puumala virus (puuv) spread, causing the zoonotic disease nephropatica epide ... | 2017 | 28770071 |
| declining ecosystem health and the dilution effect. | the "dilution effect" implies that where species vary in susceptibility to infection by a pathogen, higher diversity often leads to lower infection prevalence in hosts. for directly transmitted pathogens, non-host species may "dilute" infection directly (1) and indirectly (2). competitors and predators may (1) alter host behavior to reduce pathogen transmission or (2) reduce host density. in a well-studied system, we tested the dilution of the zoonotic puumala hantavirus (puuv) in bank voles (my ... | 2016 | 27499001 |
| leptospira spp. in small mammals from areas with low and high human hantavirus incidences in south-west germany. | leptospirosis is caused by leptospira spp. and is considered the most widespread zoonotic disease worldwide. it mimics nephropathia epidemica in humans, a disease mainly caused by puumala hantavirus (puuv). small mammals are reservoirs for leptospira spp. and puuv. seewis virus (swsv) is a shrew-borne hantavirus with unknown pathogenicity. the objective of this study was to estimate the prevalence for leptospira spp. and the frequency of leptospira-hantavirus co-infections in small mammals colle ... | 2017 | 28332927 |
| rodent host specificity of european hantaviruses: evidence of puumala virus interspecific spillover. | in order to investigate rodent host specificity of european hantaviruses, experimental infection of colonized and wild-trapped rodents was performed. in addition to the natural rodent reservoir, clethrionomys glareolus, puumala hantavirus (puuv) could infect colonized microtus agrestis and lemmus sibiricus, but not syrian hamsters or balb/c mice. neither c. glareolus, nor m. agrestis, could be readily infected by tula hantavirus (tulv). wild-trapped apodemus flavicollis and a. agrarius, the natu ... | 2002 | 12376967 |