Publications
characterization of persistent modoc viral infections in syrian hamsters. | adult syrian hamsters were readily infected by intranasal inoculation with modoc virus. viremias were detected 2 to 6 days after infection and peak viremia titers (10(6.2) plaque-forming units/ml of blood) occurred 4 days postinoculation. all infected animals developed neutralizing and hemagglutination-inhibiting antibodies by 7 days, and complement-fixing antibodies by 14 days postinoculation. high titers of antibodies persisted for at least 4 months. modoc virus was recovered from throat swabs ... | 1974 | 4211863 |
pathogenesis of modoc virus (flaviviridae; flavivirus) in persistently infected hamsters. | the long-term persistence of modoc virus (modv) infection was investigated in a hamster model. golden hamsters (mesocricetus auratus) were infected by subcutaneous inoculation with modv, in which fatal encephalitis developed in 12.5% (2 of 16). surviving hamsters shed infectious modv in their urine during the first five months after infection, and infectious modv was recovered by co-cultivation of kidney tissue up to eight months after infection. there were no histopathologic changes observed in ... | 2013 | 23358636 |