| chemotherapy of babesia microti infections in mongolian jirds. | for identifying drugs which might be effective in the treatment of human babesia microti infections, 20 selected antiprotozoal agents or combinations of agents were tested for activity against b. microti in mongolian jirds (meriones unguiculatus). 4-methyl-primaquine and aromatic diamidines, including diminazene and pentamidine, were the most effective compounds tested. | 1980 | 7447406 |
| inhibitory effects of 19 antiprotozoal drugs and antibiotics on babesia microti infection in balb/c mice. | different results have been achieved in the evaluation of antiparasitic drug activity in mongolian jirds, hamsters, and balb/c mice infected with babesia microti. the aims of the present study were to find a preferable method for drug screening and to re-evaluate the activity of several drugs against b. microti. | 2015 | 26409742 |
| transmission studies of babesia microti in ixodes ricinus ticks and gerbils. | in order to investigate the possible role of ixodes ricinus as a vector of zoonotic babesia microti infection in europe, a european rodent isolate (hk) and a zoonotic american isolate (gi) were studied in transmission experiments. pcr detected b. microti in the blood and spleens of infected gerbils (meriones unguiculatus) and also in laboratory-induced infections of i. ricinus ticks. b. microti dna was detected by pcr in all pooled samples of nymphs and the majority of adults that had fed as lar ... | 2002 | 11923342 |
| activity of atovaquone against babesia microti in the mongolian gerbil, meriones unguiculatus. | the hydroxynaphthoquinone, atovaquone (wellvone, glaxo-wellcome ltd.) was found to have significant activity against babesia microti, the main cause of human babesiosis in the u.s.a. this activity compares well with that of the most effective babesicide currently available for use in animals, imidocarb dipropionate, that unlike atovaquone is not licensed for use in humans. treatment with well tolerated doses of atovaquone results in a rapid reduction in parasitemias and an early disappearance of ... | 1999 | 10461956 |
| studies on babesia first found in murine in japan: epidemiology, morphology and experimental infection. | during the period from november 1980 to september 1982, 314 small wild mammals were captured in 5 localities in japan. twenty-six out of 86 apodemus speciosus and one out of 6 a. argenteus both species captured in shiga prefecture (35 degrees 02'n, 135 degrees 50'e, 330 m elev .) were positive for babesia. the parasitemia in those animals was generally low. the infection rate did not show any significant difference between sexes of the host or between seasons, whereas it tended to go up with the ... | 1984 | 6730782 |
| The third described case of transfusion-transmitted Babesia duncani. | BACKGROUND: Almost all of the reported US tick-borne and transfusion-associated Babesia cases have been caused by Babesia microti, which is endemic in the Northeast and upper Midwest. We investigated a case caused by B. duncani (formerly, the WA1-type parasite), in a 59-year-old California resident with sickle cell disease (HbSS) whose only risk factor for infection was receipt of red blood cell transfusions. CASE REPORT: The patient's case was diagnosed in September 2008: intraerythrocytic para ... | 2011 | 22168221 |