| an anti-idiotype antibody which mimics the inner-core region of lipopolysaccharide protects mice against a lethal challenge with endotoxin. | recently, we described the generation and characterization of an armenian hamster ab2 beta anti-idiotype monoclonal antibody (mab4g2) specific for the binding site of a mouse monoclonal antibody, maby1-4a6, directed against the conserved 2-keto-3-deoxyoctulosonate (kdo)-containing inner-core region of lipopolysaccharide (lps) (s. k. field, m. pollack, and d. c. morrison, microb. pathog. 15:103-120, 1993). in that study, mice and hamster immunized with mab4g2 generated serum immunoglobulin g and ... | 1994 | 8063418 |