Publications

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possible misidentification of mycobacterium yongonense. 201424856193
molecular taxonomic evidence for two distinct genotypes of mycobacterium yongonense via genome-based phylogenetic analysis.recently, we introduced a distinct mycobacterium intracellulare int-5 genotype, distantly related to other genotypes of m. intracellulare (int-1 to -4). the aim of this study is to determine the exact taxonomic status of the m. intracellulare int-5 genotype via genome-based phylogenetic analysis. to this end, genome sequences of the two int-5 strains, mott-h4y and mott-36y were compared with m. intracellulare atcc 13950(t) and mycobacterium yongonense dsm 45126(t). our phylogenetic analysis base ...201627031100
mycobacterium yongonense sp. nov., a slow-growing non-chromogenic species closely related to mycobacterium intracellulare.a slow-growing non-chromogenic mycobacterium was isolated from a patient with pulmonary disease. phenotypically, strain 05-1390(t) was similar to mycobacterium intracellulare atcc 13950(t). the 16s rrna gene sequence (1385 bp) of strain 05-1390(t) showed a high degree of similarity to those of the m. intracellulare complex, namely mycobacterium marseillense 5351974(t) (100 %), m. intracellulare atcc 13950(t) (99.8 %) and mycobacterium chimaera dsm 44623(t) (99.9 %). phylogenetic analysis based o ...201322427442
mycobacterium yongonense in pulmonary disease, italy. 201324206761
the development of a novel mycobacterium-escherichia coli shuttle vector system using pmyong2, a linear plasmid from mycobacterium yongonense dsm 45126t.the mycobacterium-escherichia coli shuttle vector system, equipped with the pal5000 replicon, is widely used for heterologous gene expression and gene delivery in mycobacteria. despite its extensive use, this system has certain limitations, which has led to the development of alternative mycobacterial vector systems. the present study describes the molecular structure and expression profiles of a novel 18-kb linear plasmid, pmyong2, from mycobacterium yongonense. sixteen open reading frames and ...201525822634
molecular evidence of lateral gene transfer in rpob gene of mycobacterium yongonense strains via multilocus sequence analysis.recently, a novel species, mycobacterium yongonense (dsm 45126(t)), was introduced and while it is phylogenetically related to mycobacterium intracellulare, it has a distinct rna polymerase β-subunit gene (rpob) sequence that is identical to that of mycobacterium parascrofulaceum, which is a distantly related scotochromogen, which suggests the acquisition of the rpob gene via a potential lateral gene transfer (lgt) event. the aims of this study are to prove the presence of the lgt event in the r ...201323382812
whole-genome sequence of a novel species, mycobacterium yongonense dsm 45126t.here, we report the complete genome sequence of mycobacterium yongonense dsm 45126(t), genetically closely related to the int5 genotype of m. intracellulare.201323929490
identification of ismyo2, a novel insertion sequence element of is21 family and its diagnostic potential for detection of mycobacterium yongonense.mycobacterium yongonense, as a novel member of the m. avium complex (mac), was recently reported to be isolated from human specimens in south korea and italy. due to its close relatedness to other mac members, particularly m. intracellulare in taxonomic aspects, the development of a novel diagnostic method for its specific detection is necessary for clinical or epidemiologic purposes.201526472562
role of the dna mismatch repair gene muts4 in driving the evolution of mycobacterium yongonense type i via homologous recombination.we recently showed that mycobacterium yongonense could be divided into two genotypes: type i, in which the rpob gene has been transferred from mycobacterium parascrofulaceum, and type ii, in which the rpob gene has not been transferred. comparative genome analysis of three m. yongonense type i, two m. yongonense type ii and m. parascrofulaceum type strains were performed in this study to gain insight into gene transfer from m. parascrofulaceum into m. yongonense type i strains. we found two geno ...201729326683
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