| in vitro study of antiviral activity of mycophenolic acid on brazilian orthobunyaviruses. | oropouche, caraparu, guama, guaroa and tacaiuma are ssrna viruses that belong to the genus orthobunyavirus and have been associated with human febrile illnesses and/or encephalitis. in this study, we evaluated the antiviral action of mycophenolic acid (mpa) on theseorthobunyaviruses to achieve a therapeutic agent to treat the diseases caused by these viruses. | 2007 | 17283446 |
| genetic and phylogenetic characterization of tataguine and witwatersrand viruses and other orthobunyaviruses of the anopheles a, capim, guamá, koongol, mapputta, tete, and turlock serogroups. | the family bunyaviridae has more than 530 members that are distributed among five genera or remain to be classified. the genus orthobunyavirus is the most diverse bunyaviral genus with more than 220 viruses that have been assigned to more than 18 serogroups based on serological cross-reactions and limited molecular-biological characterization. sequence information for all three orthobunyaviral genome segments is only available for viruses belonging to the bunyamwera, bwamba/pongola, california e ... | 2015 | 26610546 |
| experimental infection of golden hamsters with guama virus (peribunyaviridae, orthobunyavirus). | the guama virus (gmav) is a member of peribunyaviridae family, orthobunyavirus genus. several strains of the virus were isolated in south and central americas from several hosts, such as humans, wild animals, including nonhuman primates, wild rodents and mosquitoes as well as mice used as sentinels. the virus is able to cause febrile disease in humans. here we describe for the first time pathologic and biochemical findings in golden hamsters (mesocricetus auratus) infected with the prototype gma ... | 2019 | 31326560 |