| de novo sequencing of two new cyclic theta-defensins from baboon (papio hamadryas) leukocytes by matrix-assisted laser desorption/ionization mass spectrometry. | two cyclic theta-defensin peptides were isolated from leukocytes of the hamadryas baboon, papio hamadryas, and purified to homogeneity by gel electrophoresis and reversed-phase high-performance liquid chromatography. both peptides had high in vitro activity against escherichia coli, listeria monocytogenes, methicillin-resistant staphylococcus aureus (mrsa) and candida albicans. here, we report their de novo sequencing by matrix-assisted laser desorption/ionization tandem time-of-flight mass spec ... | 2010 | 20155756 |