| vaccination of egyptian fruit bats (rousettus aegyptiacus) with monovalent inactivated rabies vaccine. | twenty-six captive, adult egyptian fruit bats (rousettus aegyptiacus) were tested for the presence of rabies virus neutralizing antibodies (rvna) using a rapid fluorescent focus inhibition test before and after vaccination. the bats were randomly assigned into three treatment groups: group a (n = 10) bats each received one 0.1-ml dose of monovalent inactivated rabies vaccine, group b (n = 10) bats each received two 0.1-ml doses of vaccine given 30 days apart, and group c (n = 6) bats remained un ... | 2004 | 15193074 |
| functional analysis of rousettus aegyptiacus "signal transducer and activator of transcription 1" (stat1). | bats are now known as the source of several diseases in humans, but few studies regarding immune responses and factors associated with bats have so far been reported. in this study, we focused on stat1, one of the critical components in interferon (ifn)-signaling and antiviral activity, which is often targeted by viral proteins to reduce antiviral activity and increase viral replication. we found that rousettus aegyptiacus stat1 (bat stat1) is phosphorylatable and translocates to the nucleus whe ... | 2010 | 20067804 |
| induction and sequencing of rousette bat interferon alpha and beta genes. | bats are considered to be natural reservoirs for several viruses of clinical importance, including rabies virus, nipah virus, and hendra virus. type i interferons (ifns) is an important part of the immune system in the defense against viral infection. to investigate the function of type i ifns upon viral infection in bats, the nucleic acid, and amino acid sequences of egyptian rousette (rousettus aegyptiacus) ifn-alpha and -beta were characterized. sequence data indicated that bat ifn-alpha cons ... | 2008 | 18436311 |