| intraspecies diversity of sars-like coronaviruses in rhinolophus sinicus and its implications for the origin of sars coronaviruses in humans. | the chinese rufous horseshoe bat (rhinolophus sinicus) has been suggested to carry the direct ancestor of severe acute respiratory syndrome (sars) coronavirus (scov), and the diversity of sars-like covs (slcov) within this rhinolophus species is therefore worth investigating. here, we demonstrate the remarkable diversity of slcovs in r. sinicus and identify a strain with the same pattern of phylogenetic incongruence (i.e. an indication of recombination) as reported previously in another slcov st ... | 2010 | 20016037 |
| severe acute respiratory syndrome (sars) coronavirus orf8 protein is acquired from sars-related coronavirus from greater horseshoe bats through recombination. | despite the identification of horseshoe bats as the reservoir of severe acute respiratory syndrome (sars)-related coronaviruses (sarsr-covs), the origin of sars-cov orf8, which contains the 29-nucleotide signature deletion among human strains, remains obscure. although two sars-related rhinolophus sinicus bat covs (sarsr-rs-batcovs) previously detected in chinese horseshoe bats (rhinolophus sinicus) in yunnan, rsshc014 and rs3367, possessed 95% genome identities to human and civet sarsr-covs, th ... | 2015 | 26269185 |
| molecular epidemiology, evolution and phylogeny of sars coronavirus. | shortly after its emergence in southern china in 2002/2003, severe acute respiratory syndrome coronavirus (sars-cov) was confirmed to be the cause of sars. subsequently, sars-related covs (sarsr-covs) were found in palm civets from live animal markets in guangdong and in various horseshoe bat species, which were believed to be the ultimate reservoir of sarsr-cov. till november 2018, 339 sarsr-cov genomes have been sequenced, including 274 from human, 18 from civets and 47 from bats [mostly from ... | 2019 | 30844511 |