| structural and functional studies of leptins from hibernating and non-hibernating bats. | leptin, a 16-kda hormone produced by mature adipocytes, has been shown to regulate the hibernation of mammals. in this study, the leptin gene sequences of both hibernating (rhinolophus ferrumequinum) and non-hibernating (rousettus leschenaultii) bats were determined, and the leptin proteins from these two different species of bats were expressed in escherichia coli for the first time. results showed that the amino acid sequence of the leptin protein from hibernating bats had a lower degree of id ... | 2010 | 20394750 |