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cell entry by a novel european filovirus requires host endosomal cysteine proteases and niemann-pick c1.lloviu virus (llov), a phylogenetically divergent filovirus, is the proposed etiologic agent of die-offs of schreibers's long-fingered bats (miniopterus schreibersii) in western europe. studies of llov remain limited because the infectious agent has not yet been isolated. here, we generated a recombinant vesicular stomatitis virus expressing the llov spike glycoprotein (gp) and used it to show that llov gp resembles other filovirus gp proteins in structure and function. llov gp must be cleaved b ...201425310500
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