| identification of tenrec ecaudatus, a wild mammal introduced to mayotte island, as a reservoir of the newly identified human pathogenic leptospira mayottensis. | leptospirosis is a bacterial zoonosis of major concern on tropical islands. human populations on western indian ocean islands are strongly affected by the disease although each archipelago shows contrasting epidemiology. for instance, mayotte, part of the comoros archipelago, differs from the other neighbouring islands by a high diversity of leptospira species infecting humans that includes leptospira mayottensis, a species thought to be unique to this island. using bacterial culture, molecular ... | 2016 | 27574792 |
| leptospira mayottensis sp. nov., a pathogenic species of the genus leptospira isolated from humans. | a group of strains representing species of the genus leptospira, isolated from patients with leptospirosis in mayotte (indian ocean), were previously found to be considerably divergent from other known species of the genus leptospira. this was inferred from sequence analysis of rrs (16s rrna) and other genetic loci and suggests that they belong to a novel species. two strains from each serogroup currently identified within this novel species were studied. spirochaete, aerobic, motile, helix-shap ... | 2014 | 25249563 |
| a replicative plasmid vector allows efficient complementation of pathogenic leptospira strains. | leptospirosis, an emerging zoonotic disease, remains poorly understood because of a lack of genetic manipulation tools available for pathogenic leptospires. current genetic manipulation techniques include insertion of dna by random transposon mutagenesis and homologous recombination via suicide vectors. this study describes the construction of a shuttle vector, pmaori, that replicates within saprophytic, intermediate, and pathogenic leptospires. the shuttle vector was constructed by the insertio ... | 2015 | 25724960 |