| human and rodent hantavirus infection in new york state: public health significance of an emerging infectious disease. | a case of hantavirus pulmonary syndrome with possible exposure in new york and/or rhode island was confirmed in february 1994. | 1996 | 8615704 |
| evidence of hantavirus in wild rodents in northern ireland. | a survey of evidence of rodent hantavirus infection in county down, northern ireland was carried out by using immunofluorescence to detect virus antigen and antibody. antibodies to hantavirus (r22 strain of seoul virus and hantaan 76-118) were found in 11/51 (21.6%) brown rats (rattus norvegicus), 1/31 (3.2%) field mice (apodemus sylvaticus) and 17/59 (28.8%) house mice (mus domesticus). seven rodents had evidence of hantavirus antigen in lung tissues. antibody positive animals were significantl ... | 1996 | 8870634 |
| identifying rodent hantavirus reservoirs, brazil. | we describe the genetic analysis of samples from hantavirus pulmonary syndrome (hps) patients from southern and southeastern states of brazil and rodents captured at the presumed site of infection of these patients. a total of 65 samples that were antibody-positive for sin nombre or laguna negra virus by enzyme-linked immunosorbent assay were processed by nested reverse transcription-polymerase chain reaction (rt-pcr) by using several primer combinations in the m and s genome segments. pcr produ ... | 2004 | 15663849 |
| mathematical models for hantavirus infection in rodents. | hantavirus pulmonary syndrome is an emerging disease of humans that is carried by wild rodents. humans are usually exposed to the virus through geographically isolated outbreaks. the driving forces behind these outbreaks is poorly understood. certainly, one key driver of the emergence of these viruses is the virus population dynamics within the rodent population. two new mathematical models for hantavirus infection in rodents are formulated and studied. the new models include the dynamics of sus ... | 2006 | 16794943 |
| high rates of molecular evolution in hantaviruses. | hantaviruses are rodent-borne bunyaviruses that infect the arvicolinae, murinae, and sigmodontinae subfamilies of muridae. the rate of molecular evolution in the hantaviruses has been previously estimated at approximately 10(-7) nucleotide substitutions per site, per year (substitutions/site/year), based on the assumption of codivergence and hence shared divergence times with their rodent hosts. if substantiated, this would make the hantaviruses among the slowest evolving of all rna viruses. how ... | 2008 | 18417484 |
| characterization of imjin virus, a newly isolated hantavirus from the ussuri white-toothed shrew (crocidura lasiura). | until recently, the single known exception to the rodent-hantavirus association was thottapalayam virus (tpmv), a long-unclassified virus isolated from the asian house shrew (suncus murinus). robust gene amplification techniques have now uncovered several genetically distinct hantaviruses from shrews in widely separated geographic regions. here, we report the characterization of a newly identified hantavirus, designated imjin virus (mjnv), isolated from the lung tissues of ussuri white-toothed s ... | 2009 | 19357167 |
| models for the spread and persistence of hantavirus infection in rodents with direct and indirect transmission. | hantavirus, a zoonotic disease carried by wild rodents, is spread among rodents via direct contact and indirectly via infected rodent excreta in the soil. spillover to humans is primarily via the indirect route through inhalation of aerosolized viral particles. rodent-hantavirus models that include direct and indirect transmission and periodically varying demographic and epidemiological parameters are studied in this investigation. two models are analyzed, a nonautonomous system of differential ... | 2010 | 20462286 |
| detection of different south american hantaviruses. | hantaviruses are the etiologic agents of hemorrhagic fever with renal syndrome (hfrs) in old world, and hantavirus pulmonary syndrome (hps)/hantavirus cardiopulmonary syndrome (hcps), in the new world. serological methods are the most common approach used for laboratory diagnosis of hcps, however theses methods do not allow the characterization of viral genotypes. the polymerase chain reaction (pcr) has been extensively used for diagnosis of viral infections, including those caused by hantavirus ... | 2015 | 26220480 |
| a fatal hantavirus pulmonary syndrome misdiagnosed as dengue: an investigation into the first reported case in rio de janeiro state, brazil. | we report the results of an investigation into a fatal case of hantavirus pulmonary syndrome (hps) in rio de janeiro state, brazil, where the disease had not been reported previous to 2015. following the notification of an hps case, serum samples were collected from the household members and work contacts of the hps patient and tested for antibody to hantaviruses. seroprevalence of 22% (10/45) was indicated for hantavirus out of 45 human samples tested. blood and tissue samples were collected fr ... | 2017 | 28719302 |