| identification of a novel aleutian mink disease virus b-cell epitope using a monoclonal antibody against vp2 protein. | aleutian mink disease virus (amdv) is a parvovirus that causes an immune complex-mediated disease in minks. capsid protein vp2 is a major structural viral protein and can be used to diagnose amdv. in this study, a specific monoclonal antibody, 1m13, was produced against the amdv vp2 protein (amino acids 291-502). a linear vp2-protein epitope was identified by subjecting a series of partially overlapping synthesized peptides to be enzyme-linked immunosorbent assay (elisa) analysis. the results in ... | 2016 | 27354304 |
| identification and interspecies transmission of a novel bocaparvovirus among different bat species in china. | we report the discovery of a novel bocaparvovirus, bat bocaparvovirus (btbov), in one spleen, four respiratory and 61 alimentary samples from bats of six different species belonging to three families, hipposideridae, rhinolophidae and vespertilionidae. btbov showed a higher detection rate in alimentary samples of rhinolophus sinicus (5.7 %) than those of other bat species (0.43-1.59 %), supporting r. sinicus as the primary reservoir and virus spillover to accidental bat species. btbov peaked dur ... | 2016 | 27902362 |
| identification and characterization of a novel b-cell epitope on aleutian mink disease virus capsid protein vp2 using a monoclonal antibody. | aleutian mink disease is caused by a highly contagious parvovirus (aleutian mink disease virus, amdv). this disease is one of the most commercially important infectious disease worldwide and causes considerable economic losses to mink farmers. the capsid protein vp2 is the major immunogenic antigenic protein of amdv, and is involved in viral tropism, pathogenicity, and host selection. however, few reports have described the use of vp2-specific monoclonal antibodies (mabs) in b-cell epitope ident ... | 2017 | 29278728 |