| generation and characterization of monoclonal antibodies specific to avian influenza h5n1 hemagglutinin protein. | highly pathogenic avian influenza (hpai) h5n1 virus has in the past breached the species barrier from infected domestic poultry to humans in close contact. although human-to-human transmission has previously not been reported, hpai h5n1 virus has pandemic potential owing to gain of function mutation(s) and/or genetic reassortment with human influenza a viruses. monoclonal antibodies (mabs) have been used for diagnosis as well as specific therapeutic candidates in several disease conditions inclu ... | 2015 | 26683184 |
| role of terrestrial wild birds in ecology of influenza a virus (h5n1). | house sparrows, european starlings, and carneux pigeons were inoculated with 4 influenza a (h5n1) viruses isolated from different avian species. we monitored viral replication, death after infection, and transmission to uninfected contact birds of the same species. sparrows were susceptible to severe infection; 66%-100% of birds died within 4-7 days. high levels of virus were detected from oropharyngeal and cloacal swabs and in organs of deceased sparrows. inoculation of starlings caused no deat ... | 2007 | 18217557 |
| reassortant h9n2 influenza viruses containing h5n1-like pb1 genes isolated from black-billed magpies in southern china. | h9n2 influenza a viruses have become endemic in different types of terrestrial poultry and wild birds in asia, and are occasionally transmitted to humans and pigs. to evaluate the role of black-billed magpies (pica pica) in the evolution of influenza a virus, we conducted two epidemic surveys on avian influenza viruses in wild black-billed magpies in guangxi, china in 2005 and characterized three isolated black-billed magpie h9n2 viruses (bbm viruses). phylogenetic analysis indicated that three ... | 2011 | 21980538 |
| the susceptibility of magpies to a highly pathogenic avian influenza virus subtype h5n1. | korean wild magpies (pica pica sericea) were intranasally inoculated with highly pathogenic avian influenza (a/chicken/korea/es/03 virus) (h5n1), which was classified as clade 2.5. we estimated viral replication, death after infection, and histology and immunohistochemistry. this species was highly susceptible to severe infection; 100% of birds died within 5 to 8 d. the virus was detected from oropharyngeal (1 to 5 d postinfection) and cloacal (3 to 5 d postinfection) swabs from infected magpies ... | 2010 | 20460661 |
| highly pathogenic avian influenza in magpies (pica pica sericea) in south korea. | highly pathogenic avian influenza (hpai) is an extremely infectious, systemic viral disease of birds that produces high mortality and morbidity. hpai was diagnosed in the three dead magpies (pica pica sericea) submitted to the national veterinary research and quarantine service. at necropsy, the prominent lesions were multifocal or coalescing necrosis of the pancreas with enlargement of the livers and spleens. microscopically, there were severely necrotizing pancreatitis and lymphocytic meningoe ... | 2005 | 16244075 |