responses of isolator-derived japanese quail and quail cell cultures to selected animal viruses. | thirteen oncogenic and necrotizing animal viruses were assayed in life sciences, inc. (lsi)-specific pathogen-free japanese quail and lsi-specific pathogen-free chicken embryo cell cultures. nine viruses produced similar titers in the quail and chicken cell systems, whereas four viruses showed significantly higher titers in chickens. young japanese quail and chickens were inoculated with five selected avain viruses and maintained in stainless-steel isolators. comparable responses were noted in q ... | 1975 | 172527 |
fh3, a v-myc avian retrovirus with limited transforming ability. | we have isolated a new acute avian transforming virus which contains the oncogene myc. this virus, designated fh3, was isolated after injection of a 10-day-old chick embryo with avian leukosis virus. while fh3 shares many properties with other v-myc-containing avian retroviruses, it also has several unique properties. the primary target for transformation in vitro is chicken macrophages; infection of chicken fibroblasts does not lead to complete morphological transformation. fh3 also exhibits a ... | 1989 | 2555545 |
characterization of rous sarcoma virus-related sequences in the japanese quail. | we detected sequences related to the avian retrovirus rous sarcoma virus within the genome of the japanese quail, a species previously considered to be free of endogenous avian leukosis virus elements. using low-stringency conditions of hybridization, we screened a quail genomic library for clones containing retrovirus-related information. of five clones so selected, one, lambda q48, contained sequence information related to the gag, pol, and env genes of rous sarcoma virus arranged in a contigu ... | 1986 | 3016302 |
increased transcription of the c-myc oncogene in two methylcholanthrene-induced quail fibroblastic cell lines. | the expression of three c-onc genes (c-erb, c-myc, c-myb) was investigated in five cell lines established from fibrosarcomas induced with 20-methylcholanthrene (mca) of japanese quails. these cell lines showed low levels of the three c-onc genes, with the exception of two cell lines that accumulated moderate (mcaq 1-4) and large amounts (mcaq3-5) of c-myc rna. molecular cloning and restriction endonuclease analyses indicated that expression of c-myc in these two cell lines were not associated wi ... | 1984 | 6094223 |
isolation of marek's disease virus from japanese quail with lymphoproliferative disease. | sixty-one japanese quail from eight flocks with problems of recurring outbreaks of lymphoproliferative diseases resembling marek's disease (md), were examined aetiologically. gross lymphomatous lesions were seen in 17 of the quail and 11 out of 56 quail had md virus (mdv) feather tips antigens. mdv antibody was detectable in only one of 22 quail. none of 9 quail had antibodies against reticuloendotheliosis virus (rev). no mdv was isolated from the total 42 materials of quail using cell culture t ... | 1990 | 18679919 |