| genetic evidence of intercontinental movement of avian influenza in a migratory bird: the northern pintail (anas acuta). | the role of migratory birds in the movement of the highly pathogenic (hp) avian influenza h5n1 remains a subject of debate. testing hypotheses regarding intercontinental movement of low pathogenic avian influenza (lpai) viruses will help evaluate the potential that wild birds could carry asian-origin strains of hp avian influenza to north america during migration. previous north american assessments of lpai genetic variation have found few asian reassortment events. here, we present results from ... | 2008 | 19140989 |
| the survey of h5n1 flu virus in wild birds in 14 provinces of china from 2004 to 2007. | the highly pathogenic h5n1 avian influenza emerged in the year 1996 in asia, and has spread to europe and africa recently. at present, effective monitoring and data analysis of h5n1 are not sufficient in chinese mainland. | 2009 | 19742325 |
| antibodies to h5 subtype avian influenza virus and japanese encephalitis virus in northern pintails (anas acuta) sampled in japan. | blood samples from 105 northern pintails (anas acuta) captured on hokkaido, japan were tested for antibodies to avian influenza virus (aiv), japanese encephalitis virus (jev), and west nile virus (wnv) to assess possible involvement of this species in the spread of economically important and potentially zoonotic pathogens. antibodies to aiv were detected in 64 of 105 samples (61%). of the 64 positives, 95% and 81% inhibited agglutination of two different h5 aiv antigens (h5n1 and h5n9), respecti ... | 2013 | 24059097 |
| stockpiled pre-pandemic h5n1 influenza virus vaccines with as03 adjuvant provide cross-protection from h5n2 clade 2.3.4.4 virus challenge in ferrets. | avian influenza viruses, notably h5 subtype viruses, pose a continuous threat to public health due to their pandemic potential. in recent years, influenza virus h5 subtype split vaccines with novel oil-in-water emulsion based adjuvants (e.g. as03, mf59) have been shown to be safe, immunogenic, and able to induce broad immune responses in clinical trials, providing strong scientific support for vaccine stockpiling. however, whether such vaccines can provide protection from infection with emerging ... | 2017 | 28554058 |
| experimental infection of h5n1 and h5n8 highly pathogenic avian influenza viruses in northern pintail (anas acuta). | the wide geographic spread of eurasian goose/guangdong lineage highly pathogenic avian influenza (hpai) clade 2.3.4.4 viruses by wild birds is of great concern. in december 2014, an h5n8 hpai clade 2.3.4.4 group a (2.3.4.4a) virus was introduced to north america. long-distance migratory wild aquatic birds between east asia and north america, such as northern pintail (anas acuta), were strongly suspected of being a source of intercontinental transmission. in this study, we evaluated the pathogeni ... | 2018 | 29726612 |