| taxonomic reorganization of the family bornaviridae. | knowledge of bornaviruses has expanded considerably during the last decade. a possible reservoir of mammalian borna disease virus has been identified, divergent bornaviruses have been detected in birds and reptiles, and endogenous bornavirus-like elements have been discovered in the genomes of vertebrates of several species. previous sequence comparisons and alignments have indicated that the members of the current family bornaviridae are phylogenetically diverse and are not adequately classifie ... | 2015 | 25449305 |
| investigation of different infection routes of parrot bornavirus in cockatiels. | the aim of this study was to determine the natural infection route of parrot bornavirus (pabv), the causative agent of proventricular dilatation disease (pdd) in psittacines. for this purpose, nine cockatiels ( nymphicus hollandicus ) were inoculated orally, and nine cockatiels were inoculated intranasally, with a pabv-4 isolate. to compare the results of the trials, the same isolate and the same experimental design were used as in a previous study where infection was successful by intravenous a ... | 2017 | 28301249 |
| parrot bornavirus (pabv)-2 isolate causes different disease patterns in cockatiels than pabv-4. | psittaciform 1 bornavirus (pabv) has already been shown to be the aetiologic agent of proventricular dilatation disease, a significant disease of birds. however, the pathogenesis of pabv infection has not yet been resolved and valid data regarding the pathogenicity of different pabv species are lacking. thus, the present study was aimed to characterize the influence of two different pabv species on the course of disease. eighteen cockatiels were inoculated intracerebrally (i.c.) or intravenously ... | 2016 | 27100150 |
| isolation of avian bornaviruses from psittacine birds using qt6 quail cells in japan. | avian bornaviruses (abvs) were recently discovered as the causative agents of proventricular dilatation disease (pdd). although molecular epidemiological studies revealed that abvs exist in japan, no japanese isolate has been reported thus far. in this study, we isolated four strains of psittaciform 1 bornavirus from psittacine birds affected by pdd using qt6 quail cells. to our knowledge, this is the first report to isolate abvs in japan and to show that qt6 cells are available for abv isolatio ... | 2016 | 26346745 |
| distribution of viral antigen and inflammatory lesions in the central nervous system of cockatiels ( nymphicus hollandicus) experimentally infected with parrot bornavirus 2. | neurotropism is a striking characteristic of bornaviruses, including parrot bornavirus 2 (pabv-2). our study evaluated the distribution of inflammatory foci and viral nucleoprotein (n) antigen in the brain and spinal cord of 27 cockatiels ( nymphicus hollandicus) following experimental infection with pabv-2 by injection into the pectoral muscle. tissue samples were taken at 12 timepoints between 5 and 114 days post-inoculation (dpi). each experimental group had approximately 3 cockatiels per gro ... | 2019 | 30235986 |
| age-dependent development and clinical characteristics of an experimental parrot bornavirus-4 (pabv-4) infection in cockatiels (nymphicus hollandicus). | parrot bornavirus (pabv) is a pathogen often found in psittacine populations. infected, clinically healthy carrier birds are of major importance for epidemiology, but the underlying pathomechanism of this carrier status is poorly understood. the age, implying the maturation status of the immune system, at the time of infection might be significant for the clinical outcome. therefore, two groups of 11 cockatiels of different ages (adult and newly hatched) were inoculated with a pabv-4 isolate int ... | 2021 | 33215512 |