Publications

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persistence of the emerging pathogen batrachochytrium dendrobatidis outside the amphibian host greatly increases the probability of host extinction.pathogens do not normally drive their hosts to extinction; however, batrachochytrium dendrobatidis, which causes amphibian chytridiomycosis, has been able to do so. theory predicts that extinction can be caused by long-lived or saprobic free-living stages. the hypothesis that such a stage occurs in b. dendrobatidis is supported by the recent discovery of an apparently encysted form of the pathogen. to investigate the effect of a free-living stage of b. dendrobatidis on host population dynamics, ...200818048287
proteomic and phenotypic profiling of the amphibian pathogen batrachochytrium dendrobatidis shows that genotype is linked to virulence.population genetics of the amphibian pathogen batrachochytrium dendrobatidis (bd) show that isolates are highly related and globally homogenous, data that are consistent with the recent epidemic spread of a previously endemic organism. highly related isolates are predicted to be functionally similar due to low levels of heritable genetic diversity. to test this hypothesis, we took a global panel of bd isolates and measured (i) the genetic relatedness among isolates, (ii) proteomic profiles of is ...200919161465
ambient ultraviolet b radiation and prevalence of infection by batrachochytrium dendrobatidis in two amphibian species.ôçé chytridiomycosis, the emerging disease caused by the chytrid fungus batrachochytrium dendrobatidis (bd) is responsible for declines and extirpations of amphibian populations worldwide. environmental covariates modify the host-bd interaction and thus affect the ongoing spread of the pathogen. one such covariate may be the intensity of ultraviolet b (uv-b) radiation. in a field experiment conducted in laguna grande de pe+¦alara (central spain), a mountainous region where the presence of bd has ...201121676032
heritability of batrachochytrium dendrobatidis burden and its genetic correlation with development time in a population of common toad (bufo spinosus).despite the important threat that emerging pathogens pose for the conservation of biodiversity as well as human health, very little is known about the adaptive potential of host species to withstand infections. we studied the quantitative genetic architecture responsible for the burden of the fungal pathogen batrachochytrium dendrobatidis in a population of common toads in conjunction with other life-history traits (i.e., body size and development rate) that may be affected by common selective p ...201627480345
chytridiomycosis risk among central european amphibians based on surveillance data.the czech republic hosts a surprisingly rich biodiversity of amphibians representing the majority of amphibian species present in all of central and eastern europe. surveillance data of batrachochytrium dendrobatidis (bd) collected during 2008 to 2012 were analysed for basic patterns of prevalence and infection intensity among species, age groups and localities. in addition, an investigation was made into possible data bias due to varying pcr inhibition. infection prevalence in the genus pelophy ...201425392037
detection of the emerging amphibian pathogens batrachochytrium dendrobatidis and ranavirus in russia.in a population of the european common toad bufo bufo from a rural pond in the region of lake glubokoe regional reserve in moscow province, russia, unexplained mass mortality events involving larvae and metamorphs have been observed over a monitoring period of >20 yr. we tested toads from this and a nearby site for the emerging amphibian pathogens batrachochytrium dendrobatidis (bd) and ranavirus (rv). both pathogens were detected, and at the rural pond site, with the above-noted losses and decl ...201425114047
road-killed common toads (bufo bufo) in flanders (belgium) reveal low prevalence of ranaviruses and batrachochytrium dendrobatidis. 201222740561
treatment of amphibians infected with chytrid fungus: learning from failed trials with itraconazole, antimicrobial peptides, bacteria, and heat therapy.amphibian conservation goals depend on effective disease-treatment protocols. desirable protocols are species, life stage, and context specific, but currently few treatment options exist for amphibians infected with the chytrid fungus batrachochytrium dendrobatidis (bd). treatment options, at present, include antifungal drugs and heat therapy, but risks of toxicity and side-effects make these options untenable in some cases. here, we report on the comparison of several novel treatments with a mo ...201222422126
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