| attempted cross-transmission of coccidia between sheep and goats and description of eimeria ovinoidalis sp. n. | attempted infection of 2 young lambs with oocysts of eimeria christenseni from a goat was unsuccessful. negative results were obtained also when young kids were fed oocysts of eimeria ninakohlyakimovae from sheep. there was no difficulty in infecting lambs with the sheep coccidium resembling e. ninakohlyakimovae nor goats with the goat coccidium e. christenseni. oocysts from the goat measured 38.4 x 26.7 microns, but were easily distinguished from eimeria ahsata from the sheep by sporocyst size ... | 1979 | 480272 |
| ovine coccidiosis: effect of the antibiotic monensin against eimeria ninakohlyakimovae and other naturally occurring coccidia of sheep. | sixteen female and 16 male lambs were used in 4 groups to determine the effect of monensin on naturally occurring and experimentally induced coccidiosis. determinations of numbers of oocysts discharged, quantities of feces discharged, feed consumption, and weight gain were made for female and male lambs in each group. the effect of experimentally induced and naturally occurring coccidiosis on the performance of each group was compared. nonmedicated lambs, experimentally inoculated with eimeria n ... | 1978 | 629450 |
| efficacy of monensin against coccidiosis in lambs. | lambs fed monensin mixed in a complete fattening ration at concentrations of 5, 10, or 20 ppm were protected against death, impaired body weight gain, and diarrhea due to infections of eimeria ninakohlyakimovae and e ahsata. monensin given at the concentration of 10 ppm reduced oocyst passage and, at the concentration of 20 ppm, almost completely controlled oocyst passage. protection was afforded by monensin given at the concentration of 5 ppm, although oocyst passage was excessive and body weig ... | 1978 | 697157 |
| parasitism (trichostrongylus colubriformis and eimeria ninakohlyakimovae) in sheep: relationship between wool fiber diameter changes and feed conversion efficiency. | twenty-five lambs, 5 months of age, were used to compare the infection pressure of trichostrongylus colubriformis with that of eimeria ninakohlyakimovae. effects of the parasitic infection pressure were assayed by determining body weight gains, feed conversion efficiencies, and wool fiber diameter changes (reflecting changes in protein metabolism) in lambs fed a good ration and those given a marginal diet (dehydrated alfalfa pellets). significant differences in weight grains or feed conversion e ... | 1977 | 879585 |
| coccidiostatic action of monensin fed to lambs: body weight gains and feed conversion efficacy. | thirty crossbred ewe lambs weighing an average of 37.3 kg were allotted to 6 groups of 5 lambs each so that group weights were nearly equal. lambs were fed dehydrated alfalfa pellets, initially at 1.14 kg/day and subsequently increased after experimental day 15 and 42. each lamb was artificially infected with 18,000 sporulated oocysts of eimeria ninakohlyakimovae. groups 1, 2, 3, and 4 were given monensin in the form of medicated alfalfa pellets at dose levels of 5, 10, 20, and 30 g/metric ton, ... | 1976 | 1247202 |
| effect of monensin on experimental infections of eimeria ninakohlyakimovae in lambs. | two nearly identical experiments were conducted to determine the effects of the coccidiostatic compound monensin on polled dorset lambs experimentally infected with oocysts of eimeria ninakohlyakimovae. prophylactic medication at a dose level of 1 mg/kg of body weight was started 2 days before inoculation and prevented diarrhea and reduced oocyst production. therapeutic medication at a dose level of 2 mg/kg, started with the appearance of signs of infection, reduced oocyst production below that ... | 1976 | 1259229 |
| hepatic coccidiosis in the goat. | coccidial oocysts were seen in the bile from five goats infected with coccidia either naturally or artificially. the oocysts measured on average 21.3 by 18.3 microns and resembled those of eimeria ninakohlyakimovae. livers and gall bladders of infected animals showed various degrees of histopathological changes. in the worst case, bile had a thick consistency and contained blood and necrotic debris. apart from those in the bile, oocysts were seen in liver smears and in the centrilobular vein in ... | 1991 | 1894438 |
| fine structural aspects of nuclear division and merogony of eimeria ninakohlyakimovae in cultured cells. | | 1973 | 4128253 |
| fine structural aspects of early development of eimeria ninakohlyakimovae in cultured cells. | | 1972 | 4339620 |
| experimental infection of newborn lambs with eimeria ninakohlyakimovae and e. ovina. | | 1972 | 4641894 |
| experimental coccidiosis in goats. 1. experimental model. effects of parasitism on the feeding behaviour and the growth of animals; intestinal lesions. | experimentally infecting goats with three species of coccidia (eimeria ninakohlyakimovae, e. arloingi, e. christenseni) and placing them in metabolism cage helped us to obtain a parasitic development which was significant and continuous. this development is not necessarily accompanied by clinical symptoms. however slight constipation and not diarrhoea was observed. feed consumption is reduced and a subsequent reduction in the rate of growth is observed. as far as the feeding behaviour is concern ... | 1984 | 6529115 |
| oocyst discharge, rumen metabolism and performance of early weaned lambs with naturally occurring coccidiosis fed monensin. | ninety-six 9.5 kg early-weaned lambs with naturally occurring coccidiosis were fed monensin either at 0, 11, 22, or 33 mg/kg of feed for 105 days. fecal oocyst discharge during the first three days was highest with monensin 22 mg, lowest with monensin 33 mg and averaged 149.6 x 10(3) oocysts per gram feces for all lambs. monensin at 22 mg/kg of feed reduced eimeria ninakohlyakimovae and e. ahsata oocyst discharge. organic matter and crude protein digestibilities were highest (p </= 0.05) in lamb ... | 1981 | 7197187 |
| lasalocid and monensin in finishing diets for early weaned lambs with naturally occurring coccidiosis. | early weaned male crossbred lambs (n = 90) with an average weight of 14 kg were used in 6 groups to evaluate the efficacy of monensin (22 mg/g of feed) and lasalocid (12.5, 25, 50, and 100 mg/kg of feed) on naturally occurring coccidiosis. average 24-hour oocyst output at the start of the experiment ranged from 5.7 x 10(6) to 156.7 x 10(6) for monensin-treated and 100-mg lasalocid-treated groups, respectively. monensin and lasalocid were effective against eimeria ninakohlyakimovae of e ahsata. t ... | 1981 | 7271008 |
| enteric coccidia of cashmere goats in southwestern montana, usa. | a survey of enteric coccidia was made in a cashmere goat herd in montana, usa. eimerian oocysts were found in 97.2% of 616 fecal samples. newly weaned wethers and does had higher oocyst counts than yearling wethers. nine eimeria species were identified, with eimeria arloingi, eimeria ninakohlyakimovae and eimeria alijevi jointly comprising 88.3% of all oocysts recovered. these three species and eimeria hirci were present in all specimens examined. prevalence of the other species was as follows: ... | 1994 | 7886912 |
| absence of protection against eimeria ninakohlyakimovae after primo-infection with e ovinoidalis in new-born kids. | one group of kids (n = 23) was given 2 x 10(5) oocysts of eimeria ovinoidalis (sheep coccidia) at birth; a second group (n = 23) was kept as an uninoculated control. body weights, e ninakohlyakimovae oocyst output and serum coccidial antibody levels were monitored up to 77-102 d of age. no significant difference in any of these parameters was seen between the 2 groups, suggesting that no immune response to e ovinoidalis inoculation occurred. these results could be relevant to the absence of deve ... | 1994 | 8142959 |
| coccidial and helminth infections in goats kept indoors in the netherlands. | an investigation was carried out on coccidial and helminth infections in goats kept indoors on five farms in the netherlands. the goats were individually sampled. coccidial oocysts were identified and nematode eggs counted. larval cultures were made and infective larvae identified to the generic or species level. the goats were divided into three groups according to their age: kids, those weaned but not served, and older goats. oocysts were found in 26 out of 27 kids (96.3%), in 52 out of 55 wea ... | 1996 | 8720569 |
| ultrastructure of endogenous stages of eimeria ninakohlyakimovae yakimoff & rastegaieff, 1930 emend. levine, 1961 in experimentally infected goat. | the ultrastructure of endogenous stages of eimeria ninakohlyakimovae was observed in epithelial cells of cecum and colon crypts from a goat experimentally infected with 2.0 x 10(5) oocysts/kg. the secondary meronts developed above the nucleus of the host cell. the nucleus first divides and merozoites then form on the surface of multinucleated meronts. free merozoites in the parasitophorous vacuole present a conoid, double membrane, one pair of rhoptries, micronemes, micropore, anterior and poste ... | 1997 | 9361750 |
| development of eimeria ninakohlyakimovae yakimoff & rastegaieff, 1930 emend. levine, 1961 in experimentally infected goats (capra hircus). | the endogenous development and prepatent and patent periods of eimeria ninakohlyakimovae were studied in 43 1-3-wk-old coccidia-free kids inoculated with 5.0 x 10(4), 1.5 x 10(5), 2.0 x 10(5), or 9.0 x 10(5) sporulated oocysts/kg. twenty-five kids were killed at 24- or 48-hr intervals, 2-18 days after inoculation (dai). two generations of meronts, gamonts, gametes, and oocysts were found in sections stained with hematoxylin and eosin and examined using under light microscopy. the first generatio ... | 1997 | 9406771 |
| prevalence of coccidia and gastrointestinal nematode infections in cross bred goats in the dry areas of sri lanka. | the prevalence and intensity of oocysts of coccidia, particularly eimeria species, and eggs of gastrointestinal nematodes in kids (2-4 months), young goats (5-12 months) and adult goats (>1 year) were determined in five large herds managed extensively in five villages in the dry zone. of the representative samples examined, oocysts were found in 88% of kids, 91% of young goats and 83% of adults. seven species of eimeria were identified in faecal samples by salt flotation. eimeria ninakohlyakimov ... | 2001 | 11323207 |
| pathogenic effects of the coccidium eimeria ninakohlyakimovae in goats. | twenty-four coccidia-free goats were reared artificially in indoor cages and allocated to 6 groups of 4 animals each. at 20 days of age, goats in groups 1-3 received 10(4),10(5) and 10(6) sporulated oocysts of eimeria ninakohlyakimovae per goat, respectively, each as a single dose. goats in group 4 received daily doses increasing over a 3-week period, starting with 100/day for the first week, followed by 1000, and 10,000/day in weeks 2, 3, respectively. goats in group 5 received 10(4) oocysts fo ... | 2006 | 16400601 |
| influence of climatic and management factors on eimeria infections in goats from semi-arid zones. | a survey of eimeria infections was performed in dairy goats and kids (<6 months old) of six farms from a dry desert area of gran canaria island (spain). the number of oocysts per gram of faeces (opg) was determined by a modified mcmaster technique over a total of 2,616 individual faecal samples taken from the rectum in monthly intervals. eimeria oocysts were found in 96.1% of the samples with opg ranging from 1 x 10(2) to 1.4 x 10(6). kid goats had significantly (p < 0.001) higher opg counts (46 ... | 2006 | 17010046 |
| development of eimeria ninakohlyakimovae in vitro in primary and permanent cell lines. | infections with eimeria ninakohlyakimovae represent important coccidian diseases of goats severely affecting animal health and profitability of goat industry. for the development of suitable vaccination strategies basic research is needed for which one important prerequisite is the establishment of in vitro cultures guaranteeing the availability of parasitic material. therefore, primary cell cultures [caprine, bovine and human umbilical vein endothelial cells (cuvec, buvec, huvec)] as well as pe ... | 2010 | 20594648 |
| dynamic patterns of systemic innate immunity and inflammatory associated factors in experimental caprine coccidiosis. | the present study was designed to assess the dynamic patterns of pro-inflammatory cytokines, including ifn-γ, tnf-α, il-4, il-6, acute phase protein (α1-acid-glycoprotein, agp), and an inflammation associated factor (adenosine deaminase; ada) following experimental caprine coccidiosis. ten kids aging from 2 to 4 months were infected orally with 5×10(4) sporulated oocysts and 10 animals served as controls. blood samples were collected in both groups before infection and at days 3, 7, 14, 21, 28, ... | 2016 | 28095656 |
| genetic characterization and phylogenetic analysis of eimeria arloingi in iranian native kids. | among the 16 species of eimeria from goats, eimeria arloingi and eimeria ninakohlyakimovae are regarded as the most pathogenic species in the world and cause clinical caprine coccidiosis. e. arloingi is known to be an important cause of coccidiosis in iranian kids. molecular analyses of two portions of nuclear ribosomal dna (internal transcribed spacer1 (its1) and 18s rdna) were used for the genetic characterization of the e. arloingi. comparison of the sequencing data of e. arloingi obtained in ... | 2013 | 23779225 |
| gastrointestinal parasitism of goats in hilly region of meghalaya, india. | the aim of this study was to determine the prevalence of gastrointestinal (gi) parasitic infections in goats of hilly region of meghalaya. | 2017 | 28246451 |
| modulation of the pro-inflammatory molecules e-selectin and tnf-α gene transcription in eimeria ninakohlyakimovae-infected primary caprine host endothelial cells. | eimeria ninakohlyakimovae is an important coccidian parasite of goats which causes severe hemorrhagic typhlocolitis in young animals, thereby leading to high economic losses in goat industry worldwide. the first merogony of e. ninakohlyakimovae occurs within host endothelial cells (ecs) of the lacteal capillaries of the villi of the distal ileum resulting in the formation of macromeronts (up to 170 μm) within 10-12 days post-infection (p.i.) and releasing >120,000 merozoites i. the e. ninakohlya ... | 2015 | 25988828 |
| immunization with eimeria ninakohlyakimovae-live attenuated oocysts protect goat kids from clinical coccidiosis. | caprine coccidiosis, affecting mainly young goat kids around the weaning period, is worldwide the most important disease in the goat industry. control of caprine coccidiosis is increasingly hampered by resistances developed against coccidiostatic drugs leading to an enhanced need for anticoccidial vaccines. in the current study we conducted an oral immunization trial with live attenuated sporulated eimeria ninakohlyakimovae oocysts. sporulated e. ninakohlyakimovae oocysts were attenuated by x-ir ... | 2014 | 24183193 |
| isolation of an eimeria ninakohlyakimovae field strain (canary islands) and analysis of its infection characteristics in goat kids. | the current study was conducted to isolate a field strain of eimeria ninakohlyakimovae, characterize its infectivity and the response to challenge under experimental conditions. the isolated strain (gc) induced a prepatent period of 14-15 days p.i., a patency of 7±2 days and a noticeable pathogenicity in infected goat kids. challenge trials resulting in a decrease of oocysts per gram counts as well as a milder intensity of clinical signs in re-infected animals indicated the capacity of this stra ... | 2013 | 22989759 |
| protective immune responses during prepatency in goat kids experimentally infected with eimeria ninakohlyakimovae. | during the first schizogony, the goat coccidia eimeria ninakohlyakimovae develops macroschizonts in lacteal duct endothelial cells, whose rupture leads to severe ileal damage and clinical signs during the prepatent period. the immune response elicited against early stages of the parasite development still requires to be investigated. in the present study we have evaluated immune reactions in goat kids primary- and challenged-infected with eimeria ninakohlyakimovae, and sacrificed during prepaten ... | 2017 | 28606316 |
| humoral immune responses of experimentally eimeria ninakholyakimovae-infected goat kids. | although cellular immune reactions seem to be crucial for protective immune responses in eimeria spp. infections, there are also evidences on an active involvement of the humoral counterpart. in the present study, we have analyzed the humoral response of goat kids subjected to primary and challenge infections with eimeria ninakholyakimovae. specific levels of igg and igm in serum samples and iga in the ileal mucus were estimated. in infected kids, significantly increased levels of igg were obser ... | 2017 | 28504097 |
| eimeria ninakohlyakimovae induces nadph oxidase-dependent monocyte extracellular trap formation and upregulates il-12 and tnf-α, il-6 and ccl2 gene transcription. | extracellular trap (et) formation has been demonstrated as novel effector mechanism against diverse pathogens in polymorphonuclear neutrophils (pmn), eosinophils, mast cells, macrophages and recently also in monocytes. in the current study, we show that e. ninakohlyakimovae triggers the deliverance of monocyte-derived ets in vitro. fluorescence illustrations as well as scanning electron microscopy (sem) analyses showed that monocyte-derived et formation was rapidly induced upon exposure to viabl ... | 2016 | 27523951 |
| targeting essential eimeria ninakohlyakimovae sporozoite ligands for caprine host endothelial cell invasion with a phage display peptide library. | eimeria ninakohlyakimovae is an important coccidian parasite of goats which causes severe diarrhoea in young animals. specific molecules that mediate e. ninakohlyakimovae host interactions and molecular mechanisms involved in the pathogenesis are still unknown. although strong circumstantial evidence indicates that e. ninakohlyakimovae sporozoite interactions with caprine endothelial host cells (ecs) are specific, hardly any information is available about the interacting molecules that confer ho ... | 2015 | 26341796 |