| first description of hepacivirus and pegivirus infection in domestic horses in china: a study in guangdong province, heilongjiang province and hong kong district. | since 2012, three viruses, known as equine hepacivirus (eqhv), equine pegivirus (epgv) and theiler's disease-associated virus (tdav), have been discovered in equines. given that these viruses are the newest members of the flaviviridae family, genomic information concerning circulating eqhv, epgv and tdav strains around the world is limited. to date, no genetic surveillance studies have been performed on these three viruses in the equine population of china. here, a total of 177 serum samples wer ... | 2016 | 27182887 |
| hallmarks of hepatitis c virus in equine hepacivirus. | equine hepacivirus (ehcv) has been identified as a closely related homologue of hepatitis c virus (hcv) in the united states, the united kingdom, and germany, but not in asian countries. in this study, we genetically and serologically screened 31 serum samples obtained from japanese-born domestic horses for ehcv infection and subsequently identified 11 pcr-positive and 7 seropositive serum samples. we determined the full sequence of the ehcv genome, including the 3' untranslated region (utr), wh ... | 2014 | 25210167 |
| prevalence of equine hepacivirus infections in france and evidence for two viral subtypes circulating worldwide. | like hepatitis c virus (hcv) in humans, the newly identified equine hepacivirus (nphv) displays a predominating liver tropism that may evolve into chronic infections. the genomes of the two viruses share several organizational and functional features and are phylogenetically closest amongst the hepacivirus genus. a limited amount of data is available regarding the spread of hepacivirus infections in horses. in this study, we asked whether in a more representative sample the prevalence and distri ... | 2016 | 27882682 |