| a new member of the pteropine orthoreovirus species isolated from fruit bats imported to italy. | a novel member of the pteropine orthoreovirus species has been isolated and sequenced for the whole genome from flying foxes (pteropus vampyrus) imported to italy from indonesia. the new isolate named indonesia/2010 is genetically similar to melaka virus which has been the first virus of this species to be shown to be responsible for human respiratory disease. our findings highlight the importance of flying foxes as vectors of potentially zoonotic viruses and the biological hazard that lies in t ... | 2015 | 25497353 |
| characterization of a novel orthoreovirus isolated from fruit bat, china. | in recent years novel human respiratory disease agents have been described for southeast asia and australia. the causative pathogens were classified as pteropine orthoreoviruses with a strong phylogenetic relationship to orthoreoviruses of bat origin. | 2014 | 25433675 |
| pteropine orthoreovirus infection among out-patients with acute upper respiratory tract infection in malaysia. | this study aims to assess the incidence rate of pteropine orthreovirus (prv) infection in patients with acute upper respiratory tract infection (urti) in a suburban setting in malaysia, where bats are known to be present in the neighborhood. using molecular detection of prvs directly from oropharyngeal swabs, our study demonstrates that prv is among one of the common causative agents of acute urti with cough and sore throat as the commonest presenting clinical features. phylogenetic analysis on ... | 2015 | 26106066 |
| pteropine orthoreovirus: an important emerging virus causing infectious disease in the tropics? | pteropine orthoreovirus (prv) is an emerging zoonotic respiratory virus that has spilled over from bats to humans. though initially found only in bats, further case studies have found viable virus in ill patients. | 2017 | 28368854 |
| evolutionary relationship of the l- and m-class genome segments of bat-borne fusogenic orthoreoviruses in malaysia and australia. | we previously described three new malaysian orthoreoviruses designated pulau virus, melaka virus and kampar virus. melaka and kampar viruses were shown to cause respiratory disease in humans. these viruses, together with nelson bay virus, isolated from australian bats, are tentatively classified as different strains within the species pteropine orthoreovirus (prv), formerly known as nelson bay orthoreovirus, based on the small (s) genome segments. here we report the sequences of the large (l) an ... | 2011 | 21849518 |
| serological evidence of human infection with pteropine orthoreovirus in central vietnam. | pteropine orthoreovirus, potentially of bat origin, has been reported to cause respiratory tract infections among human beings in southeast asia. twelve igg elisa-positive cases with antibodies against pteropine orthoreovirus were detected among 272 human serum samples collected between march and june 2014 from in and around hue city, central vietnam. these 12 cases were igm elisa negative. neutralizing antibodies were also detected among six of these cases with the highest titer of 1:1,280 in 2 ... | 2015 | 26010233 |
| rapid whole genome sequencing of miyazaki-bali/2007 pteropine orthoreovirus by modified rolling circular amplification with adaptor ligation - next generation sequencing. | the emergence of orthoreoviruses as the causative agent of human respiratory illness over the past few years has led to a demand to determine their viral genome sequences. the whole genome sequencing of such rna viruses using traditional methods, such as sanger dideoxy sequencing following rapid amplification of cdna ends presents a laborious challenge due to the numerous preparatory steps required before sequencing can commence. we developed a practical, time-efficient novel combination method ... | 2015 | 26558341 |
| serologic assays for the detection and strain identification of pteropine orthoreovirus. | pteropine orthoreovirus (prv), potentially of bat origin, is reported to be a causative agent of emerging respiratory tract infections among humans in southeast asia. we evaluated the efficacy of serologic assays using the major outer capsid and cell attachment proteins (cap) of prv strains in the screening, confirmation and identification of three groups of human prv infections; indonesian/japanese, indonesian/hong kong and malaysian strains. the different serologic assays were tested using rab ... | 2016 | 27165561 |
| first isolation and characterization of pteropine orthoreoviruses in fruit bats in the philippines. | pteropine orthoreovirus (prv) causes respiratory tract illness (rti) in humans. prvs were isolated from throat swabs collected from 9 of 91 wild bats captured on the mindanao islands, the philippines, in 2013. the nucleic acid sequence of the whole genome of each of these isolates was determined. phylogenetic analysis based on predicted amino acid sequences indicated that the isolated prvs were novel strains in which re-assortment events had occurred in the viral genome. serum specimens collecte ... | 2017 | 28190201 |