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bovine papillomavirus type 2 infects the urinary bladder of water buffalo (bubalus bubalis) and plays a crucial role in bubaline urothelial carcinogenesis.bovine papillomavirus type 2 (bpv-2) has been shown to infect and play a role in urinary bladder carcinogenesis of buffaloes grazed on pastures with ferns from the marmara and black sea regions of turkey. bpv-2 dna has been found in both neoplastic and non-neoplastic lesions of the urinary bladder. furthermore, this virus may be a normal inhabitant of the urinary bladder since bpv-2 dna has also been detected in clinically normal buffaloes. the viral activation by fern immunosuppressant or carci ...201323100367
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