Publications

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proposed revision to the taxonomy of the genus pestivirus, family flaviviridae.we propose the creation of seven new species in the genus pestivirus (family flaviviridae) in addition to the four existing species, and naming species in a host-independent manner using the format pestivirus x. only the virus species names would change; virus isolates would still be referred to by their original names. the original species would be re-designated as pestivirus a (original designation bovine viral diarrhea virus 1), pestivirus b (bovine viral diarrhea virus 2), pestivirus c (clas ...201728786787
frequent infection of wild boar with atypical porcine pestivirus (appv).the recently identified atypical porcine pestivirus (appv) was demonstrated to be the causative agent of the neurological disorder "congenital tremor" in newborn piglets. despite its relevance and wide distribution in domestic pigs, so far nothing is known about the situation in wild boar, representing an important wild animal reservoir for the related classical swine fever virus. in this study, 456 wild boar serum samples obtained from northern germany were investigated for the presence of appv ...201829527814
prevalence and genetic diversity of atypical porcine pestivirus (appv) detected in south korean wild boars.atypical porcine pestivirus (appv), currently classified as pestivirus k, causes congenital tremor (ct) type a-ii in piglets. eighteen appv strains were identified from 2297 south korean wild boars captured in 2019. phylogenetic analysis of the structural protein e2 and nonstructural proteins ns3 and npro classified the appv viruses, including reference strains, into clades i, ii and iii. clade i was divided into four subclades; however, the strains belonging to the four subclades differed sligh ...202032599836
discovery of a novel putative atypical porcine pestivirus in pigs in the usa.pestiviruses are some of the most significant pathogens affecting ruminants and swine. here, we assembled a 11 276 bp contig encoding a predicted 3635 aa polyprotein from porcine serum with 68 % pairwise identity to that of a recently partially characterized rhinolophus affinis pestivirus (rapv) and approximately 25-28 % pairwise identity to those of other pestiviruses. the virus was provisionally named atypical porcine pestivirus (appv). metagenomic sequencing of 182 serum samples identified fo ...201526219947
atypical porcine pestivirus-a widespread virus in the swedish wild boar population.the recently identified causative agent of congenital tremor in domestic piglets, atypical porcine pestivirus (appv), was detected in serum from swedish wild boar. a previous study from sweden described appv in domestic piglets suffering from congenital tremor, but the appv situation in the wild boar population was unknown. in this study, 595 serum samples from wild boar originating from 13 counties in the south and central parts of sweden, collected between 2000 and 2018, were analysed for the ...202134331830
atypical porcine pestivirus in wild boar (sus scrofa), spain. 201830201807
atypical porcine pestivirus (appv) as a new species of pestivirus in pig production.the genus pestivirus, which belongs to the family flaviviridae, includes ssrna+ viruses responsible for infectious diseases in swine, cattle, sheep, goats, and other domestic and wild animals. recently, several putative pestiviruses species have been discovered and characterized in mammalian species (giraffe pestivirus, antelope pestivirus, hobi virus, bungowannah virus, and linda virus); one of these is a genetically distinct pestivirus, named atypical porcine pestivirus (appv), discovered usin ...201930847345
molecular survey and phylogenetic analysis of atypical porcine pestivirus (appv) identified in swine and wild boar from northern italy.atypical porcine pestivirus (appv) is a newly recognized member of the flaviviridae family. this novel porcine pestivirus was first described in 2015 in the usa, where it has been associated with congenital tremor type a-ii in new-born piglets. appv is widely distributed in domestic pigs in europe and asia. in this study, a virological survey was performed in northern italy to investigate the presence of appv using molecular methods. testing of 360 abortion samples from pig herds revealed two ap ...201931835549
new leaves in the growing tree of pestiviruses.pestiviruses are a group of viruses of veterinary importance infecting livestock animals like pigs, cattle, and sheep, and also wildlife animals like wild boar and different deer species. while for decades only four classical species (classical swine fever virus, bovine viral diarrhea virus types 1 and 2, border disease virus), and a few so-called atypical pestiviruses were known (e.g., giraffe virus, pronghorn virus, hobi virus), a series of novel pestiviruses was identified in the last years ( ...201729029724
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